Results 41 to 50 of about 87,455 (180)
New approaches to the treatment of human herpesvirus 8-associated disease. [PDF]
Human herpesvirus 8 (HHV-8, also known as Kaposi sarcoma-associated herpesvirus or KSHV) is the etiologic agent of Kaposi sarcoma (KS) and primary effusion lymphoma (PEL), as well as many cases of Castleman disease.
Alagiozoglou+76 more
core +1 more source
ABSTRACT TAFRO (thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly) syndrome is a rare, life‐threatening inflammatory condition linked to infections, neoplasms, and idiopathic multicentric Castleman disease. Interleukin (IL)‐6 inhibitors are the primary treatment, but refractory cases require alternatives. This
Serena Palmeri+10 more
wiley +1 more source
Human Herpesvirus 8-Encoded Cytokines [PDF]
Human herpesvirus (HHV)-8, also called Kaposi's sarcoma-associated herpesvirus, was discovered in 1994 and was rapidly sequenced, revealing several unique and surprising features of its genetic makeup. Among these discoveries was the identification of the first viral homolog of IL-6 and three CC/beta-chemokine ligands (viral CCL-1, -2 and -3), not ...
openaire +3 more sources
Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]
Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid+7 more
core +1 more source
Salivary Lactoferrin Is Recognized by the Human Herpesvirus-8 [PDF]
Human herpesvirus-8 (HHV-8) is commonly detected in all epidemiologic forms of Kaposi's sarcoma. Despite the broad cellular tropism of HHV-8, studies on mucosal shedding of HHV-8 have shown that infectious particles are restricted to saliva isolated from the oropharynx.
Caroline Chauvel+5 more
openaire +3 more sources
SQSTM1/p62 Orchestrates Skin Aging via USP7 Degradation
p62 exhibits diminished expression in aging skin and senescent cells. p62 serves to inhibit the accumulation of USP7 during senescence induction. The Tyr‐67 residue within the PB1 domain or Gln‐418 within the UBA domain of p62 forms a hydrogen bond with Ala‐993 of the Ubl5 domain of USP7.
Liu Chen+10 more
wiley +1 more source
Variations in Human Herpesvirus Type 8 Seroprevalence in Native Americans, South America [PDF]
To determine the epidemiology of human herpesvirus type 8 (HHV-8) among non-Amazonian native populations, we conducted a cross-sectional study in Brazil, Bolivia, and Paraquay.
Biggar+21 more
core +3 more sources
Lichen Planus Following COVID‐19 Infection and Vaccination. Matched Case–Control Study
ABSTRACT Background New‐onset lichen planus (LP) development following COVID‐19 infection/vaccination is reported. Since case series cannot be used to study exposure–outcome associations, we designed this matched case–control study to investigate whether COVID‐19‐related events and de novo LP are associated.
Paolo Giacomo Arduino+4 more
wiley +1 more source
ABSTRACT Introduction Congenital cytomegalovirus (cCMV) is a leading infectious cause of life‐long neurodevelopmental disabilities, but public awareness of CMV is low. This study evaluated a short educational video on cCMV for its acceptability and impact on pregnant women's knowledge and planned hygiene adherence.
Tanya Tripathi+10 more
wiley +1 more source
Nearly all cases of cryptococcosis in koalas are caused by Cryptococcus gattii species complex. A rare case of meningitis due to Cryptococcus neoformans VNI/AFLP1 (abbreviated VNI) is described in a koala with nasal colonisation by both species complexes.
A Teh+6 more
wiley +1 more source