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Latency of the Human Herpesviruses
Annual Review of Medicine, 1991The herpesviruses are ubiquitous pathogens that establish latent infections and can reactivate to produce recurrent disease. The fact that clinical recurrences are infrequent in most healthy individuals indicates that potent regulatory mechanisms must exist to ensure viral latency.
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Herpesviruses in human periodontal disease
Journal of Periodontal Research, 2000Recent studies have identified various herpesviruses in human periodontal disease. Epstein–Barr virus type 1 (EBV‐1) infects periodontal B‐lymphocytes and human cytomegalovirus (HCMV) infects periodontal monocytes/macrophages and T‐lymphocytes.
A, Contreras, J, Slots
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Enzymes of Human Herpesviruses
Collection of Czechoslovak Chemical Communications, 1992The properties of human herpesvirus-encoded enzymes are reviewed and the importance of sequence analysis of viral genomes as well as the experiments on characteristics of enzymes isolated from infected cell cultures are emphasized. The following enzymes are described in detail: DNA replication complex consisting of DNA polymerase, DNA helicase-primase,
Pavel Kramata, Ivan Votruba
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Human Herpesviruses in Primary Ocular Lymphoma
Leukemia and Lymphoma, 2000Several human lymphotropic herpesviruses have been found in certain lymphoproliferative disorders and implicated as possible etiologic factors or as modulating elements of the diseases. To assess a possible association of the human herpesviruses with lymphomas arising from mucosa-associated lymphoid tissue (MALT), we evaluated the presence of four ...
M Daibata, Hirokuni Taguchi, H Taguchi
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2007
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus.
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This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus.
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Testing the Susceptibility of Human Herpesviruses to Antivirals
Future Microbiology, 2009Herpesviruses cause chronic lifelong infections in humans and may cause life-threatening diseases in immunosuppressed patients. Antiviral drugs targeted to viral DNA polymerase, such as acyclovir, penciclovir, ganciclovir, foscarnet and cidofovir, are currently available and have been proven to be efficient against clinical symptoms of herpesvirus ...
Henri, Agut +4 more
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Human herpesviruses and neurological disorders of childhood
Seminars in Pediatric Neurology, 1999The human herpesviruses, a group of DNA viruses that includes herpes simplex viruses types 1 and 2, varicella zoster virus, cytomegalovirus, Epstein-Barr virus, and human herpes viruses types 6, 7, and 8, cause substantial neurological morbidity among infants and children.
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Human herpesviruses-6 and -7 infections
Current Opinion in Infectious Diseases, 2005To summarize the biology and clinical consequences of infection with the closely related human herpesviruses-6 and -7 (HHV-6/7) in children.Over the last year there has been a paucity of paediatric publications on HHV-6 and only two studies focused on HHV-7.
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Sixth Disease and the Ubiquity of Human Herpesviruses
New England Journal of Medicine, 2005Approximately three quarters of children have been infected with HHV-6 by two years of age. Dr. Charles Prober writes that a substantial proportion of the population is shedding one or more of these infectious agents, maintaining the chain of transmission and the high prevalence of infection.
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Significance of human herpesviruses to transplant recipients
Current Opinion in Infectious Diseases, 2003Despite recent great advances in transplantation techniques, herpesvirus infections remain a major cause of morbidity and mortality in transplant recipients. While improvement in immunosuppressive drug regimens have decreased the risk of graft-versus-host disease and rejection in bone marrow transplant recipients and solid organ transplant recipients ...
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