PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection [PDF]
, 2010 Dendritic cells (DCs) contribute to human immunodeficiency virus type 1 (HIV-1) transmission and dissemination by capturing and transporting infectious virus from the mucosa to draining lymph nodes, and transferring these virus particles to CD4+ T cells ...
Blay Puryear, Wendy +3 more
core +4 more sources
Factors Influencing the Binding of HIV‐1 Protease Inhibitors: Insights from Machine Learning Models
ChemMedChem, EarlyView.Machine learning unlocks the secrets of HIV‐1 protease inhibition, paving the way for data‐driven antiviral drug design. This study analyzes crystallographic data from hundreds of protein–ligand complexes, predicting ligand binding affinity with over 85% accuracy.
Yaffa Shalit, Inbal Tuvi‐Arad
wiley +1 more source
Harnessing Viral Proteases for Cellular and Molecular Engineering
Chemistry–Methods, EarlyView.Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui +2 more
wiley +1 more source
Prevalence of Human Immunodeficiency Virus Infection among Injection Drug Users Released from Jail [PDF]
Addiction and Health, 2012 Background: Injecting drug users (IDUs) and prisoners are considered to be highly vulnerable to human immunodeficiency virus (HIV) infection in Iran. This study was carried out to determine the prevalence of HIV infection among IDUs released from jail in
Ali Reza Moradi +3 more
doaj
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018 Human immunodeficiency virus (HIV) is a kind of lentivirus that infects the human immune system and could cause acquired immunodeficiency syndrome (AIDS).
Qian LIU +4 more
doaj +1 more source
Human immunodeficiency virus neutralizing antibodies and methods of use thereof [APPLICATION] [PDF]
, 2014 The invention provides broadly neutralizing antibodies directed to epitopes of Human Immunodeficiency Virus, or HIV. The invention further provides compositions containing HIV antibodies used for prophylaxis, and methods for diagnosis and treatment of ...
Bjorkman, Pamela J. +3 more
core
Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy
ChemPlusChem, EarlyView.Recent advances in the field of nucleic acid nuclear magnetic resonance (NMR) are presented. Stable isotope labeling protocols and new approaches to segmentally label nucleic acid with NMR‐active residues are summarized. The novel methods will have a strong impact on the future of nucleic acid NMR and the characterization of structure and dynamics of ...
Stefan Hilber +3 more
wiley +1 more source
Canadian Respiratory Journal, 2003 BACKGROUND: To determine whether outcomes of pneumonia among human immunodeficiency virus (HIV)-positive persons differed from those among HIV-negative persons.
David H Johnson +7 more
doaj +1 more source
Non-cryptosporidial diarrhoea in human immunodeficiency virus (HIV) infected patients. [PDF]
, 1989 G M Connolly +4 more
openalex +1 more source
Anatomic Fat Depots and Coronary Plaque Among Human Immunodeficiency Virus-Infected and Uninfected Men in the Multicenter AIDS Cohort Study. [PDF]
, 2016 Methods. In a cross-sectional substudy of the Multicenter AIDS Cohort Study, noncontrast cardiac computed tomography (CT) scanning for coronary artery calcium (CAC) scoring was performed on all men, and, for men with normal renal function, coronary CT ...
Brown, Todd T +8 more
core +1 more source