Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder+4 more
wiley +1 more source
Should We Advance Our Understanding of Immunoglobulin E in Viral Immunity?
Immunoglobulin E has been extensively studied in allergies and parasitic diseases. Antigen‐specific IgE has been identified as part of the humoral response to viruses. This revision speculates on possible functionalities for IgE, such as neutralisation, cytotoxicity and immunopathology of viral diseases, and provide insights about gaps to fill in ...
Amanda Izeli Portilho+3 more
wiley +1 more source
Conformations of membrane human immunodeficiency virus (HIV-1) envelope glycoproteins solubilized in Amphipol A18 lipid-nanodiscs. [PDF]
Zhang S+6 more
europepmc +1 more source
Secrets and Their Consequences in Heathcare: A Scoping Review of Worker Experiences
ABSTRACT Aims To explore current knowledge of the nature of secrets healthcare consumers reveal to healthcare workers and the impact on the healthcare worker experience resulting from these private disclosures. Design Scoping review. Data Sources Eight electronic databases were searched for studies published between 1980 and 2025 that met the inclusion
Kiriaki Stewart+3 more
wiley +1 more source
Human Papillomavirus Vaccination Rates in Patients Living With Human Immunodeficiency Virus (HIV). [PDF]
Boivin N, Desai S.
europepmc +1 more source
Exploring the Impact of COVID‐19 on Acute Care Nurses: An Integrative Review
ABSTRACT Aim To analyse, critique, and synthesise available research to create a unique framework of the impacts of COVID‐19 on acute care nurses. Methods Whittemore and Knafl's framework was used to organise this review. The Mixed Methods Appraisal Tool was used for quality analysis.
Janelle Schentag+2 more
wiley +1 more source
Composite Burkitt Lymphoma and Classical Hodgkin Lymphoma in an Human Immunodeficiency Virus (HIV)-Positive Patient. [PDF]
Smith D+4 more
europepmc +1 more source
ABSTRACT Aim To explore the perspectives and experiences of maternity care providers regarding obstetric violence across low‐, middle‐, and high‐income countries. Design An integrative review of the literature. Methods A systematic literature search in CINAHL, Medline (via Ovid), SCOPUS, and the Cochrane Library was conducted from 2014 to 2024. Further
Emma C. Collins+3 more
wiley +1 more source
Perceptions and Acceptance of a Prophylactic Vaccine for Human Immunodeficiency Virus (HIV): A Qualitative Study. [PDF]
Aldhouse NVJ+6 more
europepmc +1 more source
Dysregulation of miR‐21‐5p in diabetic nephropathy and its role in inflammatory response
The level of serum miR‐21‐5p was significantly upregulated in DN patients. The expression level of miR‐21‐5p increased with the aggravation of DN. Downregulation of miR‐21‐5p reduced HG‐induced cell proliferation. Downregulation OF miR‐21‐5P reduced HG‐induced levels of proinflammatory factors.
Yujiang Zhang, Qin Deng, Jianping Yi
wiley +1 more source