PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection [PDF]
, 2010 Dendritic cells (DCs) contribute to human immunodeficiency virus type 1 (HIV-1) transmission and dissemination by capturing and transporting infectious virus from the mucosa to draining lymph nodes, and transferring these virus particles to CD4+ T cells ...
Blay Puryear, Wendy +3 more
core +9 more sources
Characterization of a novel type of HIV-1 particle assembly inhibitor using a quantitative Luciferase-Vpr packaging-based assay [PDF]
, 2011 The HIV-1 auxiliary protein Vpr and Vpr-fusion proteins can be copackaged with Gag precursor (Pr55Gag) into virions or membrane-enveloped virus-like particles (VLP).
Elisabeth Errazuriz +9 more
core +12 more sources
Understanding the process of envelope glycoprotein incorporation into virions in simian and feline immunodeficiency viruses [PDF]
, 2014 The lentiviral envelope glycoproteins (Env) mediate virus entry by interacting with specific receptors present at the cell surface, thereby determining viral tropism and pathogenesis.
Affranchino, Jose Luis +1 more
core +4 more sources
Has HIV evolved to induce immune pathogenesis? [PDF]
, 2008 Human immunodeficiency virus (HIV) induces a chronic generalized activation of the immune system, which plays an important role in the pathogenesis of AIDS.
Bartha, István +2 more
core +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Restriction of HIV-1 replication in monocytes is abolished by Vpx of SIVsmmPBj. [PDF]
PLoS ONE, 2009 BACKGROUND: Human primary monocytes are refractory to infection with the human immunodeficiency virus 1 (HIV-1) or transduction with HIV-1-derived vectors.
Silke Schüle +7 more
doaj +1 more source
Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection. [PDF]
, 2007 BackgroundWe reported previously on the emergence and clinical implications of simian immunodeficiency virus (SIVmac251) mutants with a K65R mutation in reverse transcriptase (RT), and the role of CD8+ cell-mediated immune responses in suppressing ...
Bischofberger, Norbert +10 more
core +3 more sources
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
EPIDEMIOLOGICAL ASPECTS OF THE INCIDENCE OF HIV INFECTION IN THE RUSSIAN FEDERATION AND KUZBASS
Медицина в Кузбассе, 2022 Human immunodeficiency virus (HIV infection) is one of the most severe non-epidemic and socially caused infectious diseases worldwide. HIV infection is an infectious anthroponotic chronic disease caused by the human immunodeficiency virus, slowly ...
Андрей Георгиевич Петров +5 more
doaj
Adolescente com Vírus da Imunodeficiência Humana – compreendendo crenças e valores da família
Rev Rene, 2017 Objective: to understand how the beliefs and values of the families of HIV-positive adolescents for Human Immunodeficiency Virus influence family dynamics.
Patrícia Neyva da Costa Pinheiro +5 more
doaj +1 more source