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Human Leukocyte Antigen (HLA) [PDF]

, 2019
Early-onset (pediatric and adolescent) multiple sclerosis (MS) is a chronic autoimmune and neurodegenerative disorder of the central nervous system, which accounts for 3–5% of all MS cases.
B. Mahdi
semanticscholar   +3 more sources

Accurate imputation of human leukocyte antigens with CookHLA [PDF]

Nature Communications, 2021
The recent development of imputation methods enabled the prediction of human leukocyte antigen (HLA) alleles from intergenic SNP data, allowing studies to fine-map HLA for immune phenotypes.
Seungho Cook, Wanson Choi, Hyunjoon Lim, Yang Luo, K. Kim, Xiaoming Jia, S. Raychaudhuri, B. Han   +7 more
semanticscholar   +4 more sources

The human leukocyte antigen system … simplified

Global Journal of Transfusion Medicine, 2017
Human leukocyte antigen (HLA) and transfusion medicine go hand in hand. Transfusion medicine experts are involved in transplants, particularly hematopoietic stem cell transplant.
Anand Deshpande
doaj   +2 more sources

Plasma-derived proteomic biomarkers in human leukocyte antigen-haploidentical or human leukocyte antigen-matched bone marrow transplantation using post-transplantation cyclophosphamide

Haematologica, 2017
Recent studies have suggested that plasma-derived proteins may be potential biomarkers relevant for graft-versus-host disease and/or non-relapse mortality occurring after allogeneic blood or marrow transplantation.
Christopher G. Kanakry, Giorgos Bakoyannis, Susan M. Perkins, Shannon R. McCurdy, Ante Vulic, Edus H. Warren, Etienne Daguindau, Taylor Olmsted, Christen Mumaw, Andrea M.H. Towlerton, Kenneth R. Cooke, Paul V. O’Donnell, Heather J. Symons, Sophie Paczesny, Leo Luznik   +14 more
doaj   +2 more sources

The expression of human leukocyte antigen by human ejaculated spermatozoa [PDF]

Molecular Genetics & Genomic Medicine, 2019
Background After coitus and insemination, an inflammatory response is evident in the female reproductive tract (FRT). Semen contains a variety of immune‐activating components that have a major role in the induction of an immune response in the FRT.
Nasrin Sereshki, Alireza Andalib, Ataollah Ghahiri, Ferdos Mehrabian, Roya Sherkat, Abbas Rezaei, David Wilkinson   +6 more
doaj   +4 more sources

Human Leukocyte Antigen Diversity: A Southern African Perspective

Journal of Immunology Research, 2015
Despite the increasingly well-documented evidence of high genetic, ethnic, and linguistic diversity amongst African populations, there is limited data on human leukocyte antigen (HLA) diversity in these populations.
Mqondisi Tshabalala, Juanita Mellet, Michael S. Pepper   +2 more
doaj   +2 more sources

Classification of Human Leukocyte Antigen (HLA) Supertypes [PDF]

Methods in molecular biology, 2014
Identification of new antigenic peptides, derived from infectious agents or cancer cells, which bind to human leukocyte antigen (HLA) class I and II molecules, is of importance for the development of new effective vaccines capable of activating the ...
Mingjun Wang, M. Claesson
semanticscholar   +4 more sources

Breast cancer, viruses, and human leukocyte antigen (HLA) [PDF]

Scientific Reports
Several viruses have been implicated in breast cancer, including human herpes virus 4 (HHV4), human herpes virus 5 (HHV5), human papilloma virus (HPV), human JC polyoma virus (JCV), human endogenous retrovirus group K (HERVK), bovine leukemia virus (BLV)
Lisa M. James, Apostolos P. Georgopoulos
doaj   +2 more sources

Human Leukocyte Antigens in Pregnancy and Preeclampsia [PDF]

Frontiers in Genetics, 2022
Preeclampsia is a pregnancy-induced hypertensive disorder, the pathophysiology of which includes underlying maternal cardiovascular disease, deficient spiral artery remodeling during placenta development, and inflammatory immune responses at the maternal-fetal interface.
Aisagbonhi, Omonigho, Morris, Gerald P
openaire   +4 more sources

Simultaneous genotyping for human platelet antigen systems and HLA-A and HLA-B loci by targeted next-generation sequencing

Frontiers in Immunology, 2022
In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang, Jielin Wang, Xuan You, Xuan You, Yanmin He, Yanmin He, Xiaozhen Hong, Xiaozhen Hong, Ji He, Ji He, Sudan Tao, Sudan Tao, Faming Zhu, Faming Zhu   +13 more
doaj   +1 more source