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The human leukocyte antigen system … simplified

open access: yesGlobal Journal of Transfusion Medicine, 2017
Human leukocyte antigen (HLA) and transfusion medicine go hand in hand. Transfusion medicine experts are involved in transplants, particularly hematopoietic stem cell transplant.
Anand Deshpande
doaj   +2 more sources

The expression of human leukocyte antigen by human ejaculated spermatozoa [PDF]

open access: yesMolecular Genetics & Genomic Medicine, 2019
Background After coitus and insemination, an inflammatory response is evident in the female reproductive tract (FRT). Semen contains a variety of immune‐activating components that have a major role in the induction of an immune response in the FRT.
Nasrin Sereshki   +6 more
doaj   +4 more sources

Breast cancer, viruses, and human leukocyte antigen (HLA) [PDF]

open access: yesScientific Reports
Several viruses have been implicated in breast cancer, including human herpes virus 4 (HHV4), human herpes virus 5 (HHV5), human papilloma virus (HPV), human JC polyoma virus (JCV), human endogenous retrovirus group K (HERVK), bovine leukemia virus (BLV)
Lisa M. James, Apostolos P. Georgopoulos
doaj   +2 more sources

Human Leukocyte Antigens in Pregnancy and Preeclampsia [PDF]

open access: yesFrontiers in Genetics, 2022
Preeclampsia is a pregnancy-induced hypertensive disorder, the pathophysiology of which includes underlying maternal cardiovascular disease, deficient spiral artery remodeling during placenta development, and inflammatory immune responses at the maternal-fetal interface.
Aisagbonhi, Omonigho, Morris, Gerald P
openaire   +4 more sources

Simultaneous genotyping for human platelet antigen systems and HLA-A and HLA-B loci by targeted next-generation sequencing

open access: yesFrontiers in Immunology, 2022
In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang   +13 more
doaj   +1 more source

Human leukocyte antigen-A, B, and DRB1 diversity in renal transplant patients and donors: A single-center retrospective observational study

open access: yesIndian Journal of Transplantation, 2022
Background: The understanding of transplant acceptance or rejection derives directly from knowing human leukocyte antigen (HLA) involved in the immune response.
Vikash Chandra Mishra   +5 more
doaj   +1 more source

Frequency of class 1 human leukocyte antigen allele subtypes in Egyptian patients with idiopathic uveitis

open access: yesJournal of the Egyptian Ophthalmological Society, 2023
Bacground Idiopathic uveitis is the most common uveitis type and is viewed as an inconclusive diagnosis for patients as well as physicians. Human leukocyte antigen (HLA) typing helps in understanding the pathogenesis of several diseases.
Dina M.R Bahgat   +4 more
doaj   +1 more source

Early Blood Transfusion After Kidney Transplantation Does Not Lead to dnDSA Development: The BloodIm Study

open access: yesFrontiers in Immunology, 2022
Outcomes after kidney transplantation are largely driven by the development of de novo donor-specific antibodies (dnDSA), which may be triggered by blood transfusion.
Thomas Jouve   +11 more
doaj   +1 more source

High fraction of silent recombination in a finite population two-locus neutral birth-death-mutation model [PDF]

open access: yesPhys. Rev. E 106, 024409 (2022), 2021
A precise estimate of allele and haplotype polymorphism is of great interest in theoretical population genetics, but also has practical applications, such as bone marrow registries management. Allele polymorphism is driven mainly by point mutations, while haplotype polymorphism is also affected by recombination. Current estimates treat recombination as
arxiv   +1 more source

Human leukocyte antigen-B alleles in spondyloarthritides: A single-center, prospective, cross-sectional study

open access: yesIndian Journal of Rheumatology, 2022
Objective: The objective of this study is to study distribution of human leukocyte antigen (HLA)-B alleles in Spondyloarthritis (SpA) and to find its clinical relevance in the patient management.
Jeet Hemantkumar Patel   +5 more
doaj   +1 more source

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