Results 101 to 110 of about 348,506 (362)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Intrinsic feature between malignant tumor cells and human normal leukocytes with statistical decision tree analysis via Raman spectroscopy [PDF]

open access: yesarXiv, 2020
In this study, the combination of a developing data mining technique called statistical decision tree analysis method and Raman spectroscopy was proposed to differentiate human normal leukocytes from malignant tumor cells. Statistical results obtained indicate this method possesses an admirable performance of a mean classification accuracy of 94.43% on
arxiv  

Expression of the CD6 T lymphocyte differentiation antigen in normal human brain [PDF]

open access: yes, 1990
Antigens shared by the immune and central nervous systems (CNS) have been described repeatedly. The present study reports the expression of the CD6 lymphocyte differentiation antigen in normal human brain evidenced by immunohistochemistry and Northern ...
Funke, Ilona   +4 more
core   +1 more source

Melanoma and Human Leukocyte Antigen (HLA): Immunogenicity of 69 HLA Class I Alleles With 11 Antigens Expressed in Melanoma Tumors

open access: yesCancer Informatics, 2023
Host immunogenetics play a critical role in the human immune response to melanoma, influencing both melanoma prevalence and immunotherapy outcomes. Beneficial outcomes that stimulate T cell response hinge on binding affinity and immunogenicity of human ...
Apostolos P Georgopoulos   +3 more
doaj   +1 more source

Hydrogen sulfide repairs testicular damage induced by heat stress in rats

open access: yesFEBS Open Bio, EarlyView.
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo   +6 more
wiley   +1 more source

Isolation, phenotype, and allostimulatory activity of mouse liver dendritic cells [PDF]

open access: yes, 1994
Donor liver-derived dendritic cells (DC) have recently been identified within various lymphoid and nonlymphoid tissues of organ allograft recipients, including nonimmunosuppressed mice transplanted with and permanently accepting major histocompatibility ...
Li, Y   +6 more
core   +1 more source

Overview of Human Leukocyte Antigen Development at Siriraj Hospital

open access: yesSiriraj Medical Journal, 2017
No ...
Dasnayanee Chandanayingyong
doaj  

Analysis of non-HLA genomic risk factors in HLA-matched unrelated donor hematopoietic cell transplantation for chronic myeloid leukemia

open access: yesHaematologica, 2012
Background Allogeneic hematopoietic cell transplantation is the main curative therapy for patients with chronic myeloid leukemia who do not respond to tyrosine kinase inhibitors.
Kim F. Pearce   +10 more
doaj   +1 more source

Classification of Human Leukocyte Antigen (HLA) Supertypes [PDF]

open access: yes, 2014
Identification of new antigenic peptides, derived from infectious agents or cancer cells, which bind to human leukocyte antigen (HLA) class I and II molecules, is of importance for the development of new effective vaccines capable of activating the cellular arm of the immune response.
Wang, Mingjun, Claesson, Mogens H
openaire   +3 more sources

Assessment of concurrent neoplasms and a paraneoplastic association in MOGAD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Cases of myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD) co‐occurring with neoplasms have been reported. In this international, retrospective cohort study in South Korea and the USA, 16 of 445 (3.6%) patients with MOGAD had concurrent neoplasm within 2 years of MOGAD onset, resulting in a standardized incidence ...
Young Nam Kwon   +24 more
wiley   +1 more source

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