Results 151 to 160 of about 595,560 (387)

Importance of killer immunoglobulin-like receptors in allogeneic hematopoietic stem cell transplantation

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2011
Hematopoietic stem cell transplantation is the treatment of choice for many hematologic diseases, such as multiple myeloma, bone marrow aplasia and leukemia.
Danilo Santana Alessio Franceschi   +5 more
doaj   +1 more source

Identification of the sequence required for expression of the 2H4 epitope on the human leukocyte common antigens. [PDF]

open access: bronze, 1987
Michel Streuli   +4 more
openalex   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

open access: yesAdvanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen   +2 more
wiley   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

open access: yesAdvanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi   +5 more
wiley   +1 more source

Human leukocyte antigens (HLA) and mycobacterial disease [PDF]

open access: bronze, 1988
René R. P. de Vries   +2 more
openalex   +1 more source

Multivariate Screening and Automated Clustering of Macrophage Immunoreactome to Nanoparticles and Photothermal Therapy

open access: yesAdvanced Science, EarlyView.
Predicting immune responses to treatments, including nanomedicines, with high throughput test is challenging due to the immunoreactome's complexity and plasticity. A predictive screening platform integrating pathway activation and gene profiling in macrophages has been developed as a versatile tool for designing effective immunotherapies.
Sonia Becharef   +12 more
wiley   +1 more source

Applicability of an instrument to identify human leukocyte antigen-compatible donors for platelet transfusions

open access: yesHematology, Transfusion and Cell Therapy, 2018
Background: The selection of compatible human leukocyte antigen platelets has been associated with improved platelet increments. Therefore, an effective strategy would be the selection of donors who are genetically compatible according to the human ...
Millena Gomes Ferreira   +7 more
doaj  

Enhancing Natural Killer and CD8 + T Cell-Mediated Anticancer Cytotoxicity and Proliferation of CD8 + T Cells with HLA-E Monospecific Monoclonal Antibodies [PDF]

open access: yes, 2019
Cytotoxic NK/CD8+ T cells interact with MHC-I ligands on tumor cells through either activating or inhibiting receptors. One of the inhibitory receptors is CD94/NKG2A.
Asgharzadeh, Shahab   +3 more
core   +1 more source

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

open access: yesAdvanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li   +8 more
wiley   +1 more source

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