Results 11 to 20 of about 348,506 (362)

Human Leukocyte Antigens in Pregnancy and Preeclampsia [PDF]

open access: yesFrontiers in Genetics, 2022
Preeclampsia is a pregnancy-induced hypertensive disorder, the pathophysiology of which includes underlying maternal cardiovascular disease, deficient spiral artery remodeling during placenta development, and inflammatory immune responses at the maternal-fetal interface.
Aisagbonhi, Omonigho, Morris, Gerald P
openaire   +3 more sources

Simultaneous genotyping for human platelet antigen systems and HLA-A and HLA-B loci by targeted next-generation sequencing

open access: yesFrontiers in Immunology, 2022
In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang   +13 more
doaj   +1 more source

Human leukocyte antigen-A, B, and DRB1 diversity in renal transplant patients and donors: A single-center retrospective observational study

open access: yesIndian Journal of Transplantation, 2022
Background: The understanding of transplant acceptance or rejection derives directly from knowing human leukocyte antigen (HLA) involved in the immune response.
Vikash Chandra Mishra   +5 more
doaj   +1 more source

Frequency of class 1 human leukocyte antigen allele subtypes in Egyptian patients with idiopathic uveitis

open access: yesJournal of the Egyptian Ophthalmological Society, 2023
Bacground Idiopathic uveitis is the most common uveitis type and is viewed as an inconclusive diagnosis for patients as well as physicians. Human leukocyte antigen (HLA) typing helps in understanding the pathogenesis of several diseases.
Dina M.R Bahgat   +4 more
doaj   +1 more source

Early Blood Transfusion After Kidney Transplantation Does Not Lead to dnDSA Development: The BloodIm Study

open access: yesFrontiers in Immunology, 2022
Outcomes after kidney transplantation are largely driven by the development of de novo donor-specific antibodies (dnDSA), which may be triggered by blood transfusion.
Thomas Jouve   +11 more
doaj   +1 more source

High fraction of silent recombination in a finite population two-locus neutral birth-death-mutation model [PDF]

open access: yesPhys. Rev. E 106, 024409 (2022), 2021
A precise estimate of allele and haplotype polymorphism is of great interest in theoretical population genetics, but also has practical applications, such as bone marrow registries management. Allele polymorphism is driven mainly by point mutations, while haplotype polymorphism is also affected by recombination. Current estimates treat recombination as
arxiv   +1 more source

Human leukocyte antigen-B alleles in spondyloarthritides: A single-center, prospective, cross-sectional study

open access: yesIndian Journal of Rheumatology, 2022
Objective: The objective of this study is to study distribution of human leukocyte antigen (HLA)-B alleles in Spondyloarthritis (SpA) and to find its clinical relevance in the patient management.
Jeet Hemantkumar Patel   +5 more
doaj   +1 more source

HLA predictions from the bronchoalveolar lavage fluid samples of five patients at the early stage of the Wuhan seafood market COVID-19 outbreak [PDF]

open access: yesBioinformatics, btaa756 (2020), 2020
We are in the midst of a global viral pandemic, one with no cure and a high mortality rate. The Human Leukocyte Antigen (HLA) gene complex plays a critical role in host immunity. We predicted HLA class I and II alleles from the transcriptome sequencing data prepared from the bronchoalveolar lavage fluid samples of five patients at the early stage of ...
arxiv   +1 more source

Association of HLA-B27 antigen with clinical and laboratory parameters in patients with juvenile idiopathic arthritis [PDF]

open access: yesMedicinski Glasnik, 2023
Aim To analyse the association of human leukocyte antigen B27 with clinical and laboratory parameters in patients with juvenile idiopathic arthritis (JIA) at the disease onset. Methods A retrospective review of medical records of 25 HLAB27 positive and
Adisa Čengić   +5 more
doaj   +1 more source

Human leukocyte antigen-C and killer immunoglobulin-like receptors in reproductive medicine

open access: yesMedwave, 2021
Proper communication between natural killer cells and the human leukocyte antigens of the embryonic trophoblast at the maternal-fetal interface during pregnancy is essential for successful reproduction.
Edgard Rodríguez de Frías   +6 more
doaj   +1 more source

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