Results 11 to 20 of about 595,560 (387)

Human Leukocyte Antigen (HLA) System: Genetics and Association with Bacterial and Viral Infections

Journal of Immunological Research, 2022
The human leukocyte antigen (HLA) system is one of the most crucial host factors influencing disease progression in bacterial and viral infections. This review provides the basic concepts of the structure and function of HLA molecules in humans. Here, we
Sadeep Medhasi, N. Chantratita
semanticscholar   +1 more source

Human leukocyte antigen-A, B, and DRB1 diversity in renal transplant patients and donors: A single-center retrospective observational study

Indian Journal of Transplantation, 2022
Background: The understanding of transplant acceptance or rejection derives directly from knowing human leukocyte antigen (HLA) involved in the immune response.
Vikash Chandra Mishra, Dinesh Chandra, Trupti Deshpande, Parvind Singh, Archana Anthwal, Vimarsh Raina   +5 more
doaj   +1 more source

Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry

Hepatology, 2021
Genetic predisposition to autoimmune hepatitis (AIH) in adults is associated with possession of human leukocyte antigen (HLA) class I (A*01, B*08) and class II (DRB1*03, ‐04, ‐07, or ‐13) alleles, depending on geographic region. Juvenile autoimmune liver
Yun Ma, Haibin Su, M. Yuksel, M. Longhi, M. Mcphail, Pengyun Wang, S. Bansal, G. Wong, J. Graham, Li Yang, Richard J Thompson, D. Doherty, N. Hadžić, Y. Zen, A. Quaglia, M. Heneghan, M. Samyn, D. Vergani, G. Mieli-Vergani   +18 more
semanticscholar   +1 more source

Frequency of class 1 human leukocyte antigen allele subtypes in Egyptian patients with idiopathic uveitis

Journal of the Egyptian Ophthalmological Society, 2023
Bacground Idiopathic uveitis is the most common uveitis type and is viewed as an inconclusive diagnosis for patients as well as physicians. Human leukocyte antigen (HLA) typing helps in understanding the pathogenesis of several diseases.
Dina M.R Bahgat, Alaa A Gad, Walid R Kosmass, Mariam R Fadel, Fatma H Abdelraouf   +4 more
doaj   +1 more source

Early Blood Transfusion After Kidney Transplantation Does Not Lead to dnDSA Development: The BloodIm Study

Frontiers in Immunology, 2022
Outcomes after kidney transplantation are largely driven by the development of de novo donor-specific antibodies (dnDSA), which may be triggered by blood transfusion.
Thomas Jouve, Thomas Jouve, Johan Noble, Johan Noble, Hamza Naciri-Bennani, Céline Dard, Dominique Masson, Gaëlle Fiard, Gaëlle Fiard, Paolo Malvezzi, Lionel Rostaing, Lionel Rostaing   +11 more
doaj   +1 more source

Human Leukocyte Antigen Susceptibility Map for Severe Acute Respiratory Syndrome Coronavirus 2

Journal of Virology, 2020
Individual genetic variation may help to explain different immune responses to a virus across a population. In particular, understanding how variation in HLA may affect the course of COVID-19 could help identify individuals at higher risk from the ...
Austin Nguyen, Julianne K. David, Sean K. Maden, Mary A. Wood, Benjamin R. Weeder, Abhinav Nellore, Reid F. Thompson   +6 more
semanticscholar   +1 more source

Human leukocyte antigen-B alleles in spondyloarthritides: A single-center, prospective, cross-sectional study

Indian Journal of Rheumatology, 2022
Objective: The objective of this study is to study distribution of human leukocyte antigen (HLA)-B alleles in Spondyloarthritis (SpA) and to find its clinical relevance in the patient management.
Jeet Hemantkumar Patel, Ved Chaturvedi, Lalit Duggal, Neeraj Jain, Gurbir Bhandari, Monika Jain   +5 more
doaj   +1 more source

Human leukocyte antigen susceptibility map for SARS-CoV-2

medRxiv, 2020
We probe how genetic variability across the three major histocompatibility complex (MHC) class I genes (human leukocyte antigen [HLA] A, B, and C) may affect susceptibility to and severity of severe acute respiratory syndrome 2 (SARS-CoV-2), the virus ...
Austin Nguyen, Julianne K. David, Sean K. Maden, Mary A. Wood, Benjamin R. Weeder, Abhinav Nellore, Reid F. Thompson   +6 more
semanticscholar   +1 more source

Human Leukocyte Antigen B*14:01 and B*35:01 Are Associated With Trimethoprim‐Sulfamethoxazole Induced Liver Injury

Hepatology, 2020
Trimethoprim (TMP)–sulfamethoxazole (SMX) is an important cause of idiosyncratic drug‐induced liver injury (DILI), but its genetic risk factors are not well understood.
Yi-Ju Li, E. Phillips, A. Dellinger, P. Nicoletti, R. Schutte, Danmeng Li, D. Ostrov, R. Fontana, P. Watkins, A. Stolz, A. Daly, G. Aithal, H. Barnhart, N. Chalasani   +13 more
semanticscholar   +1 more source

Human leukocyte antigen-G upregulates immunoglobulin-like transcripts and corrects dysfunction of immune cells in immune thrombocytopenia

Haematologica, 2020
Human leukocyte antigen-G is a non-classical major histocompatibility complex class I antigen with potent immune-inhibitory function. Human leukocyte antigen-G benefit patients in allotransplantation and autoimmune diseases by interacting with its ...
Xin Li, Zi Sheng, Yuanxin Sun, Yuanjian Wang, Miao Xu, Zhiyue Zhang, Hui Li, Linlin Shao, Yanqi Zhang, Jinming Yu, Chunhong Ma, Chengjiang Gao, Ming Hou, Heyu Ni, Jun Peng, Ji Ma, Qi Feng   +16 more
doaj   +1 more source