Results 241 to 250 of about 658,106 (408)

Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives

American Journal of Hematology, EarlyView.
ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica, Devin K. Binder, Meinrad Drexel, Chrysanthy Ikonomidou, Shilpa D. Kadam, Guenther Sperk, Christian Steinhäuser   +6 more
wiley   +1 more source

Sequence Conservation in Potential Regulatory Regions of the Mouse and Human Leukocyte Common Antigen Gene

, 1989
Nancy Johnson, Claudia Meyer, Jeanette T. Pingel, M L Thomas   +3 more
openalex   +1 more source

Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex molecules. [PDF]

, 1996
Ofer Mandelboim, Hugh T. Reyburn, Mar Valés‐Gómez, L Pazmany, Marco Colonna, Giovanna Borsellino, J L Strominger   +6 more
openalex   +1 more source

A Transcriptome‐Wide Mendelian Randomization Study in Isolated Human Immune Cells Highlights Risk Genes Involved in Viral Infections and Potential Drug Repurposing Opportunities for Schizophrenia

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey, Liam Gaziano, Preethi Eldi, Catherine Toben, Beben Benyamin, S. Hong Lee, Elina Hyppönen   +6 more
wiley   +1 more source

HU LY-M3—A HUMAN LEUKOCYTE ANTIGEN

, 1983
Hilary Vaughan, Christopher H. Thompson, ROSEMARY L. SPARRO, Ian F. C. McKenzie   +3 more
openalex   +1 more source

Molecular characterization of antigenic polymorphisms (Ond(a) and Mart(a)) of the beta 2 family recognized by human leukocyte alloantisera [PDF]

, 1996
Suat Şimşek, CE van der Schoot, M Daams, Elly Huiskes, Mary Clay, John McCullough, C. van der Plas‐van Dalen, David F. Stroncek, AE von dem Borne   +8 more
openalex   +1 more source

Comparison of the pathogenicity and neutrophil and monocyte response between SARS‐CoV‐2 prototype and Omicron BA.1 in a lethal mouse model

Animal Models and Experimental Medicine, EarlyView.
We conducted clinical characterization studies and performed virological evaluations on mice infected with SARS‐CoV‐2 prototype and Omicron BA.1 using RT‐PCR, HE and immunohistochemistry staining. We also studied the alterations of neutrophils and monocytes caused by the two strains using complete blood count, immunohistochemistry, and flow cytometry ...
Na Rong, Jing Wu, Binbin Zhao, Wanjun Peng, Hekai Yang, Gengxin Zhang, Dangting Ruan, Xiaohui Wei, Jiangning Liu   +8 more
wiley   +1 more source

Association of human leukocyte antigen-B1*03 with cervical cancer in Japanese women aged 35 years and younger [PDF]

, 1995
Akihiro Nawa, Yukihiro Nishiyama, Takaaki Kobayashi, Yasunori Wakahara, Tomomitsu Okamoto, Fumitaka Kikkawa, Nobuhiko Suganuma, Setsuko Goto, Kazuo Kuzuya, Yutaka Tomoda   +9 more
openalex   +1 more source

Human Leukocyte Antigen-Disease Associations in Rheumatoid Arthritis.

Rheumatic Disease Clinics of North America, 2017
V. van Drongelen, J. Holoshitz
semanticscholar   +1 more source