Animal lectins as cell adhesion molecules [PDF]
Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
core +1 more source
Predicting Kidney Transplant Survival using Multiple Feature Representations for HLAs [PDF]
Kidney transplantation can significantly enhance living standards for people suffering from end-stage renal disease. A significant factor that affects graft survival time (the time until the transplant fails and the patient requires another transplant) for kidney transplantation is the compatibility of the Human Leukocyte Antigens (HLAs) between the ...
arxiv
Studies on the Contact Sensitization of Man with Simple Chemicals [PDF]
Dinitrochlorobenzene (DNCB) coupled to peripheral blood erythrocytes or leukocytes forms a particulate complex, DNCB-antigen. The addition of DNCB-antigen induced blastogenesis and DNA synthesis in leukocyte cultures from DNCB-sensitized human subjects ...
Levis, William R.+2 more
core +1 more source
HLA Class I (A and B) Allele Polymorphism in a Moroccan Population Infected with Hepatitis C Virus
Hepatitis C virus (HCV) infection is one of the major health burdens worldwide. Its course depends on the virus itself and the host’s immune responses.
Safa Machraoui+6 more
doaj +1 more source
Objectives: Here, we show two probable haplotypes associated with the human leukocyte antigen (HLA) DRB1*13:50:01 allele. The haplotypes were observed from 41 randomized unrelated Taiwanese individuals among a population of 23,064 individuals tested ...
Nondumiso Ayanda Mazibuko+1 more
doaj +1 more source
A Latent Space Model for HLA Compatibility Networks in Kidney Transplantation [PDF]
Kidney transplantation is the preferred treatment for people suffering from end-stage renal disease. Successful kidney transplants still fail over time, known as graft failure; however, the time to graft failure, or graft survival time, can vary significantly between different recipients.
arxiv
Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]
Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Abdi R+34 more
core +1 more source
A Case of Diamond Blackfan Anemia with Mutation in Ribosomal Protein S19 [PDF]
Diamond Blackfan Anemia (DBA) is a rare disorder which presents with anemia in early infancy. This disorder is genetically and clinically heterogeneous in nature. The inheritance is mainly autosomal dominant.
John Solomon+5 more
doaj +1 more source
TripHLApan: predicting HLA molecules binding peptides based on triple coding matrix and transfer learning [PDF]
Human leukocyte antigen (HLA) is an important molecule family in the field of human immunity, which recognizes foreign threats and triggers immune responses by presenting peptides to T cells. In recent years, the synthesis of tumor vaccines to induce specific immune responses has become the forefront of cancer treatment.
arxiv
Microchimerism, dendritic cell progenitors and transplantation tolerance [PDF]
The recent discovery of multilineage donor leukocyte microchimerism in allograft recipients up to three decades after organ transplantation implies the migration and survival of donor stem cells within the host.
Demetris, AJ+5 more
core +1 more source