Results 31 to 40 of about 595,560 (387)
Improving Access to HLA-Matched Kidney Transplants for African American Patients
Frontiers in Immunology, 2022 IntroductionKidney transplants fail more often in Black than in non-Black (White, non-Black Hispanic, and Asian) recipients. We used the estimated physicochemical immunogenicity for polymorphic amino acids of donor/recipient HLAs to select weakly ...
Dulat Bekbolsynov +8 more
doaj +1 more source
Expression of the CD6 T lymphocyte differentiation antigen in normal human brain [PDF]
, 1990 Antigens shared by the immune and central nervous systems (CNS) have been described repeatedly. The present study reports the expression of the CD6 lymphocyte differentiation antigen in normal human brain evidenced by immunohistochemistry and Northern ...
Funke, Ilona +4 more
core +1 more source
Experimental and Molecular Medicine, 2019 Pluripotent stem cell transplantation is a promising regenerative strategy for treating intractable diseases. However, securing human leukocyte antigen (HLA)-matched donor stem cells is extremely difficult.
Y. Jang +6 more
semanticscholar +1 more source
Kourami: graph-guided assembly for novel human leukocyte antigen allele discovery
Genome Biology, 2018 Accurate typing of human leukocyte antigen (HLA) is important because HLA genes play important roles in immune responses and disease genesis. Previously available computational methods are database-matching approaches and their outputs are inherently ...
Heewook Lee, Carl Kingsford
semanticscholar +1 more source
Maternal and infant infections stimulate a rapid leukocyte response in breastmilk [PDF]
, 2013 Breastmilk protects infants against infections; however, specific responses of breastmilk immune factors to different infections of either the mother or the infant are not well understood. Here, we examined the baseline range of breastmilk leukocytes and
Filgueira, L +6 more
core +3 more sources
The Emerging Roles of Human Leukocyte Antigen-F in Immune Modulation and Viral Infection
Frontiers in Immunology, 2019 Human leukocyte antigens (HLAs) play various critical roles in both innate and adaptive immunity through processes such as presenting antigens to T cells and serving as ligands for receptors expressed on natural killer (NK) cells.
A. Lin, Wei-Hua Yan
semanticscholar +1 more source
Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]
, 2004 Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Abdi R +34 more
core +1 more source
Frontiers in Immunology, 2017 The genetic factors associated with susceptibility or resistance to viral infections are likely to involve a sophisticated array of immune response. These genetic elements may modulate other biological factors that account for significant influence on ...
Nicole B. Crux, S. Elahi
semanticscholar +1 more source
Not All Antibodies Are Created Equal: Factors That Influence Antibody Mediated Rejection. [PDF]
, 2017 Consistent with Dr. Paul Terasaki's "humoral theory of rejection" numerous studies have shown that HLA antibodies can cause acute and chronic antibody mediated rejection (AMR) and decreased graft survival. New evidence also supports a role for antibodies
Butler, Carrie L +3 more
core +7 more sources
Haematologica, 2012 Background Polymorphic differences between donor and recipient human leukocyte antigen class I molecules can result in graft-versus-host disease due to distinct peptide presentation. As part of the peptide-loading complex, tapasin plays an important role
Soumya Badrinath +6 more
doaj +1 more source