Results 51 to 60 of about 595,560 (387)

Association of human leukocyte antigen class II alleles with severe Middle East respiratory syndrome-coronavirus infection

open access: yesAnnals of Thoracic Medicine, 2016
Background: Middle East Respiratory Syndrome (MERS) is a disease of the lower respiratory tract and is characterized by high mortality. It is caused by a beta coronavirus (CoV) referred to as MERS-CoV.
A. Hajeer   +4 more
semanticscholar   +1 more source

Back to the future [PDF]

open access: yes, 2005
Sin ...
Bach   +32 more
core   +3 more sources

Cytokine profile in COVID-19 infection: focus on interleukin-13, interleukin-33, and tumor necrosis factor-α as immunological markers

open access: yesItalian Journal of Medicine
COVID-19 is a pandemic disease that has a wide spectrum of symptoms from asymptomatic to severe fatal cases due to hyperactivation of the immune system and secretion of pro-inflammatory cytokines.
Huda Saleem   +3 more
doaj   +1 more source

Successful renal re-transplantation in the presence of pre-existing anti-DQ5 antibodies when there was zero mismatch at class I human leukocyte antigen A, B, & C: a case report

open access: yesJournal of Medical Case Reports, 2009
Introduction Hyperacute rejection may be prevented by avoiding the transplantation of kidneys into patients with pre-existing anti-donor Class I human leukocyte antigen antibodies.
Hartono John   +6 more
doaj   +1 more source

Human leukocyte antigen typing and crossmatch: A comprehensive review

open access: yesWorld journal of transplantation, 2017
Renal transplantation remains the best option for patients suffering from end stage renal disease (ESRD). Given the worldwide shortage of organs and growing population of patients with ESRD, those waitlisted for a transplant is ever expanding ...
M. Althaf   +4 more
semanticscholar   +1 more source

Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80(dim), CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients [PDF]

open access: yes, 1996
We have shown previously that granulocyte-macrophage colony-stimulating factor-stimulated mouse bone marrow-derived MHC class II+ dendritic cell (DC) progenitors that are deficient in cell surface expression of the costimulatory molecules B7-1 (CD8O) and
Angus W. Thomson   +48 more
core   +1 more source

Alloantibody Generation and Effector Function Following Sensitization to Human Leukocyte Antigen

open access: yesFrontiers in Immunology, 2016
Allorecognition is the activation of the adaptive immune system to foreign human leukocyte antigen (HLA) resulting in the generation of alloantibodies.
M. Hickey, N. Valenzuela, E. Reed
semanticscholar   +1 more source

Human Leukocyte Antigen–G and Cancer Immunoediting [PDF]

open access: yesCancer Research, 2008
Abstract Immunosurveillance is an extrinsic mechanism of cancer suppression that eliminates nascent tumors. However, the selection imposed by immunosurveillance can drive tumor evolution and the emergence of clinically apparent neoplasms.
Urosevic, M, Dummer, R
openaire   +3 more sources

Tumor-reactive immune cells protect against metastatic tumor and induce immunoediting of indolent but not quiescent tumor cells [PDF]

open access: yes, 2016
Two major barriers to cancer immunotherapy include tumor-induced immune suppression mediated by myeloid-derived suppressor cells and poor immunogenicity of the tumor-expressing self-antigens.
Bear, Harry D.   +8 more
core   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

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