Results 111 to 120 of about 8,960,514 (293)
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
GOD'S IMAGE AND LIKENESS IN HUMANS AND OTHER ANIMALS: PERFORMATIVE SOUL‐MAKING AND GRACED NATURE
Although official Roman Catholic teaching affirms the concept of evolution as a convincing theory in order to explain the biological origin of different life forms, there is still a strong insistence on an “ontological gap” between human beings and all ...
doaj +2 more sources
Macrophage-Like Properties of Human Hyalocytes
The cortical layer of the vitreous body of the eye contains a homogeneous population of hyalocytes. These cells were prepared from human autopsy eyes under sterile conditions by incubating the vitreous gel in tissue culture medium containing 300 micrograms/ml hyaluronidase. With the use of trypan blue staining, 60% to 90% of the cells were viable; they
G, Grabner, G, Boltz, O, Förster
openaire +3 more sources
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
What shapes user engagement with bot-like accounts on social Media? Evidence from Twitter
Users on social media platforms increasingly encounter and interact with automated accounts. While prior research has mainly examined how social bots operate and shape online environments, less is known about how human users contribute to human-bot ...
Xinxue Liu +4 more
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Artificial intelligence is undergoing rapid transformations, and its application in education has gradually expanded. In particular, the educational effect of artificial intelligence chatbots in English learning has steadily become prominent.
Wenbo Wei, An Zhao, Hongning Ma
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Too real for comfort? Uncanny responses to computer generated faces
As virtual humans approach photorealistic perfection, they risk making real humans uncomfortable. This intriguing phenomenon, known as the uncanny valley, is well known but not well understood.
Green, Robert D. +3 more
core +1 more source

