Results 81 to 90 of about 8,960,514 (293)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Exploring the Effectiveness of Evaluation Practices for Computer-Generated Nonverbal Behaviour
Applied SciencesThis paper compares three methods for evaluating computer-generated motion behaviour for animated characters: two commonly used direct rating methods and a newly designed questionnaire.
Pieter Wolfert +2 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Deriving authenticity from artificial intelligence : assessing the roles of human-likeness and influencer tier in virtual influencer marketing [PDF]
This dissertation explores the strategic use of virtual influencers to facilitate popularization of an emerging technology, non-fungible tokens (NFTs).
Looi, Jie Min
core +1 more source
Drug Likeness Screening of Black Soybean Flavonoids
, 2023 Screening of drug-likeness and toxicity of compounds contained in black soybeans. A) Screening for drug-likeness, B) Toxicity screening, C) 2D structure of compounds that pass the screening.
Ricadonna Raissa (12081878) +1 more
core +1 more source
Masked-speech Recognition Using Human and Synthetic Cloned Speech
Trends in HearingVoice cloning is used to generate synthetic speech that mimics vocal characteristics of human talkers. This experiment used voice cloning to compare human and synthetic speech for intelligibility, human-likeness, and perceptual similarity, all tested in ...
Lauren Calandruccio +3 more
doaj +1 more source
Koers : Bulletin for Christian Scholarship, 2008 Imago et similitudo Dei: the meaning of humans being God’s image and likeness investigated from a Christianphilosophical perspective This investigation is an effort to determine the meaning of the Biblical revelation that human beings were created in ...
B.J. van der Walt
doaj +1 more source
Human-likeness and attribution of intentionality predict vicarious sense of agency over humanoid robot actions. [PDF]
Sci Rep, 2022 Roselli C +3 more
europepmc +1 more source