Results 71 to 80 of about 19,365 (259)

Judging Others by Your Own Standards: Attractiveness of Primate Faces as Seen by Human Respondents

open access: yesFrontiers in Psychology, 2018
The aspects of facial attractiveness have been widely studied, especially within the context of evolutionary psychology, which proposes that aesthetic judgements of human faces are shaped by biologically based standards of beauty reflecting the mate ...
Silvie Rádlová   +2 more
doaj   +1 more source

CRH-Like Peptides in Human Reproduction

open access: yesCurrent Medicinal Chemistry, 2009
CRH and Urocortins 1, 2 and 3 comprise the, so far identified, members of the CRH family of peptides in humans. Their actions are mediated through two distinct receptors, CRHR1 and CRHR2, encoded by different genes.
Zoumakis, E.   +2 more
openaire   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The humanism in the thought and in the spirituality of saint Bernard of Clairvaux: The fundamental attitude discovered in cistercian mystics and cistercian art

open access: yesThe Person and the Challenges
This paper is dedicated to humanism in the thought, spirituality and teaching of Saint Bernard. Bernard’s way of thinking and his spiritual, interior life were the object of study by many scholars.
Dariusz Tabor
doaj   +1 more source

A physicochemical descriptor-based scoring scheme for effective and rapid filtering of kinase-like chemical space

open access: yesJournal of Cheminformatics, 2012
Background The current chemical space of known small molecules is estimated to exceed 1060 structures. Though the largest physical compound repositories contain only a few tens of millions of unique compounds, virtual screening of databases of this size ...
Singh Narender   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Digital Twin-Based Alternate Ego Modeling and Simulation: Eva Herzigová as a 3D MetaHuman Avatar

open access: yesEngineering Management in Production and Services
Due to Dimension Studios and Unsigned Group, by likeness and movement digitization, the human supermodel Eva Herzigová’s highly realistic metahuman and 3D digital twin lead to perpetual career extension (e.g., on virtual runway shows by catwalk ...
Lăzăroiu George   +3 more
doaj   +1 more source

Human-like Navigation in a World Built for Humans

open access: yesCoRR
When navigating in a man-made environment they haven't visited before--like an office building--humans employ behaviors such as reading signs and asking others for directions. These behaviors help humans reach their destinations efficiently by reducing the need to search through large areas. Existing robot navigation systems lack the ability to execute
Bhargav Chandaka   +5 more
openaire   +2 more sources

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