Results 71 to 80 of about 131,492 (236)
Too real for comfort? Uncanny responses to computer generated faces [PDF]
, 2014 As virtual humans approach photorealistic perfection, they risk making real humans uncomfortable. This intriguing phenomenon, known as the uncanny valley, is well known but not well understood.
Green, Robert D. +3 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
SCRIPTed: A Journal of Law, Technology & Society, 2004 This article is concerned with the commercial appropriation of human personality and its regulation in different legal systems. Where accepted, so called “publicity rights” allow for the exclusive commercial exercise of a persona’s publicity values.
Olaf Weber
doaj +3 more sources
Masked-speech Recognition Using Human and Synthetic Cloned Speech
Trends in HearingVoice cloning is used to generate synthetic speech that mimics vocal characteristics of human talkers. This experiment used voice cloning to compare human and synthetic speech for intelligibility, human-likeness, and perceptual similarity, all tested in ...
Lauren Calandruccio +3 more
doaj +1 more source
Journal of Cheminformatics, 2012 Background The current chemical space of known small molecules is estimated to exceed 1060 structures. Though the largest physical compound repositories contain only a few tens of millions of unique compounds, virtual screening of databases of this size ...
Singh Narender +5 more
doaj +1 more source
Human-likeness and attribution of intentionality predict vicarious sense of agency over humanoid robot actions. [PDF]
Sci Rep, 2022 Roselli C +3 more
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Robot Voices in Daily Life: Vocal Human-Likeness and Application Context as Determinants of User Acceptance. [PDF]
Front Psychol, 2022 Schreibelmayr S, Mara M.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Docking and QSAR Studies of Camptothecin Derivatives as Inhibitor of DNA Topoisomerase-I [PDF]
, 2011 Camptothecin (CPT) is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme Topoisomerase-I (Topo-I) and has shown remarkable anticancer activity in preliminary clinical trials. The major limitation is its low solubility and high adverse reaction.
Dharmendra K. Yadav +2 more
core +2 more sources