Results 141 to 150 of about 1,287,033 (265)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Mustard derived compounds as insecticides and modulators of human metabolism. [PDF]

Sci Rep
Garg S, Punetha H, Gangola S, Vyas A, Mittal A, Tariq M, Saiyad M, Menaa F, Alkhaibari AM, Alrasheedi N, Hamida MBB.   +10 more
europepmc   +1 more source

Human metabolism and excretion kinetics of benzotriazole UV stabilizer UV-327 after single oral administration. [PDF]

Arch Toxicol, 2023
Fischer C, Leibold E, Hiller J, Göen T.
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Molecular Pharmacology of Human Metabolism Diseases. [PDF]

Int J Mol Sci
Bułdak Ł.
europepmc   +1 more source

Revving an Engine of Human Metabolism: Activity Enhancement of Triosephosphate Isomerase via Hemi-Phosphorylation. [PDF]

ACS Chem Biol, 2022
Schachner LF, Soye BD, Ro S, Kenney GE, Ives AN, Su T, Goo YA, Jewett MC, Rosenzweig AC, Kelleher NL.   +9 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Human Metabolism of Sirolimus Revisited. [PDF]

Metabolites
Davari B, Shokati T, Ward AM, Nguyen V, Klawitter J, Klawitter J, Christians U.   +6 more
europepmc   +1 more source

Design of highly sensitive biosensors using hollow-core microstructured fibers for plasma sensing in aids with human metabolism. [PDF]

Opt Quantum Electron, 2023
Alam MK, Vadivel K, Natesan A, Sghaireen MG, Ganji KK, Srivastava KC, Nashwan S, Khader Y.   +7 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source