Results 151 to 160 of about 1,287,033 (265)

Cold exposure and human metabolism: A heterogeneous response across tissues and organs. [PDF]

Temperature (Austin)
Tetzlaff EJ, Hancock C, Waddell L, Gagnon SS, Mäkelä KA, Karhu T, Peltonen JE, Herzig KH, Gagnon DD.   +8 more
europepmc   +1 more source

Meal Timing and Macronutrient Composition Modulate Human Metabolism and Reward-Related Drive to Eat. [PDF]

Nutrients, 2022
Chamorro R, Kannenberg S, Wilms B, Kleinerüschkamp C, Meyhöfer S, Park SQ, Lehnert H, Oster H, Meyhöfer SM.   +8 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Insights into the human metabolism and in silico receptor activity of gidazepam and desalkylgidazepam. [PDF]

Arch Toxicol
Gameli PS, Kutzler J, Minnelli C, Basile G, Laudadio E, Busardò FP, Auwärter V, Carlier J.   +7 more
europepmc   +1 more source

A dynamic multi-tissue model to study human metabolism. [PDF]

NPJ Syst Biol Appl, 2021
Martins Conde P, Pfau T, Pires Pacheco M, Sauter T.   +3 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

A genetic map of human metabolism across the allele frequency spectrum. [PDF]

Nat Genet
Zoodsma M, Beuchel C, Yasmeen S, Kohleick L, Nepal A, Koprulu M, Kronenberg F, Mayr M, Williamson A, Pietzner M, Langenberg C.   +10 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

C11orf54 catalyzes L-xylulose formation in human metabolism. [PDF]

Proc Natl Acad Sci U S A
Malatesta M, De Rito C, Gasparini F, Merici G, Dell'Accantera D, Quilici G, Sansone F, Percudani R.   +7 more
europepmc   +1 more source

The role of the super-relaxed state of myosin in human metabolism. [PDF]

Metabol Open, 2021
Wilson C, Naber N, Cooke R.
europepmc   +1 more source