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Impact of antibiotics on the human microbiome and consequences for host health
MicrobiologyOpen, 2022 It is well established that the gut microbiota plays an important role in host health and is perturbed by several factors including antibiotics. Antibiotic‐induced changes in microbial composition can have a negative impact on host health including ...
D. Patangia +4 more
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The microbiome as a human organ [PDF]
Clinical Microbiology and Infection, 2012 The human organism is a complex structure composed of cells belonging to all three domains of life on Earth, Eukarya, Bacteria and Archaea, as well as their viruses. Bacterial cells of more than a thousand taxonomic units are condensed in a particular functional collective domain, the intestinal microbiome.
Baquero, Fernando, Nombela, César
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mSphere, 2022 Renal impairment associated with chronic kidney disease (CKD) causes the buildup of uremic toxins that are deleterious to patient health. Current therapies that manage toxin accumulation in CKD offer an incomplete therapeutic effect against toxins such ...
Gerrit A. Stuivenberg +4 more
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Identifying biases and their potential solutions in human microbiome studies
Microbiome, 2021 Advances in DNA sequencing technology have vastly improved the ability of researchers to explore the microbial inhabitants of the human body. Unfortunately, while these studies have uncovered the importance of these microbial communities to our health ...
Jacob T. Nearing, A. Comeau, M. Langille
semanticscholar +1 more source
Access Microbiology, 2021 A microbiome is defined as the aggregate of all microbiota that reside in human digestive system and other tissues. This microbiota includes viruses, bacteria, fungi that live in various human organs and tissues like stomach, guts, oesophagus, mouth cavity, urinary tract, vagina, lungs, and skin.
Mohammad Menati Rashno +3 more
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Gut Microbes, 2022 Biogeographic variations in the gut microbiota are pivotal to understanding the global pattern of host–microbiota interactions in prevalent lifestyle-related diseases. Pakistani adults, having an exceptionally high prevalence of type 2 diabetes mellitus (
Afshan Saleem +9 more
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Public human microbiome data are dominated by highly developed countries
PLoS Biology, 2022 The importance of sampling from globally representative populations has been well established in human genomics. In human microbiome research, however, we lack a full understanding of the global distribution of sampling in research studies.
Richard J. Abdill +2 more
semanticscholar +1 more source
Context and the human microbiome [PDF]
Microbiome, 2015 Human microbiome reference datasets provide epidemiological context for researchers, enabling them to uncover new insights into their own data through meta-analyses. In addition, large and comprehensive reference sets offer a means to develop or test hypotheses and can pave the way for addressing practical study design considerations such as sample ...
McDonald, Daniel +2 more
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The microbiome and human cancer
Science, 2021 BACKGROUND Historical accounts linking cancer and microbes date as early as four millennia ago. After establishment of the germ theory of infectious diseases, clinical research of microbial influences on cancer began in 1868, when William Busch reported spontaneous tumor regressions in patients with
Gregory D. Sepich-Poore +5 more
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Cosmetics, 2020 The skin microbiome is in a very close mutualistic relationship with skin cells, influencing their physiology and immunology and participating in many dermatological conditions.
Tiziana Ciardiello +4 more
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