Results 31 to 40 of about 239,936 (333)
Enterotypes of the human gut microbiome [PDF]
Nature, 2011 Our knowledge of species and functional composition of the human gut microbiome is rapidly increasing, but it is still based on very few cohorts and little is known about variation across the world. By combining 22 newly sequenced faecal metagenomes of individuals from four countries with previously published data sets, here we identify three robust ...
Arumugam, Manimozhiyan +83 more
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Screening of Bacteriophage Encoded Toxic Proteins with a Next Generation Sequencing-Based Assay
Viruses, 2021 Bacteriophage vB_EcoM_fHy-Eco03 (fHy-Eco03 for short) was isolated from a sewage sample based on its ability to infect an Escherichia coli clinical blood culture isolate.
Jutta Kasurinen +4 more
doaj +1 more source
Enrichment of gut microbiome strains for cultivation-free genome sequencing using droplet microfluidics [PDF]
Cell Reports Methods 12/2021, 2021 We report a droplet microfluidic method to target and sort individual cells directly from complex microbiome samples, and to prepare these cells for bulk whole genome sequencing without cultivation. We characterize this approach by recovering bacteria spiked into human stool samples at a ratio as low as 1:250 and by successfully enriching endogenous ...
arxiv +1 more source
Microorganisms, 2023 Fecal microbiota transplantation (FMT) has shown highly variable results in indications beyond recurrent Clostridioides difficile infection. Microbiota dysbiosis in many diseases is characterized by the depletion of strictly anaerobic bacteria, which may
Berta Bosch +5 more
doaj +1 more source
Ancient human microbiomes [PDF]
Journal of Human Evolution, 2015 Very recently, we discovered a vast new microbial self: the human microbiome. Our native microbiota interface with our biology and culture to influence our health, behavior, and quality of life, and yet we know very little about their origin, evolution, or ecology.
Christina Warinner +3 more
openaire +3 more sources
Infant gut microbiota restoration: state of the art
Gut Microbes, 2022 The gut microbiota has a central role in the programming of the host’s metabolism and immune function, with both immediate and long-term health consequences.
Katri Korpela, Willem M. de Vos
doaj +1 more source
Gut Microbes, 2022 Birth mode and maternal intrapartum (IP) antibiotics affect infants’ gut microbiota development, but their relative contribution to absolute bacterial abundances and infant health has not been studied.
Roosa Jokela +9 more
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Gut Microbes, 2023 Fecal microbiota transplantation (FMT) is used routinely to treat recurrent Clostridioides difficile infection (rCDI) and investigated as a treatment for numerous conditions associated with gut microbiota alterations.
Aki Ronkainen +5 more
doaj +1 more source
HT-MMIOW: A Hypothesis Test approach for Microbiome Mediation using Inverse Odds Weighting [PDF]
arXiv, 2023 The human microbiome has an important role in determining health. Mediation analyses quantify the contribution of the microbiome in the causal path between exposure and disease; however, current mediation models cannot fully capture the high dimensional, correlated, and compositional nature of microbiome data and do not typically accommodate ...
arxiv
Variable selection for sparse Dirichlet-multinomial regression with an application to microbiome data analysis [PDF]
Annals of Applied Statistics 2013, Vol. 7, No. 1, 418-442, 2013 With the development of next generation sequencing technology, researchers have now been able to study the microbiome composition using direct sequencing, whose output are bacterial taxa counts for each microbiome sample. One goal of microbiome study is to associate the microbiome composition with environmental covariates.
arxiv +1 more source