Results 71 to 80 of about 239,936 (333)

Unlocking the Gates: A Novel Diagnostic Molecule for Quantifying Efflux Levels in Gram‐Positive Bacteria

open access: yesAdvanced Healthcare Materials, EarlyView.
Efflux‐mediated resistance compromises antibiotic efficacy, yet rapid detection remains elusive. This study presents a novel phenazinium‐based diagnostic molecule for quantifying bacterial efflux levels in Gram‐positive pathogens. The optimized compound enables precise, real‐time efflux assessment using fluorescence and colorimetric techniques ...
Mrunal Patil   +15 more
wiley   +1 more source

Efficacy of lyophilized Lactobacillus sakei as a potential candidate for preventing carbapenem-resistant Klebsiella infection

open access: yesAnnals of Microbiology
Background Antimicrobial resistance is considered one of the greatest threats to human health, according to the World Health Organization (WHO). Gram-negative bacteria, especially carbapenem-resistant Enterobacteriaceae (CRE), have become a significant ...
Hanieh Tajdozian   +12 more
doaj   +1 more source

Applying Genomic Epidemiology to Characterize a COVID-19 Outbreak in a Developmentally Disabled Adult Group Home Setting, Arizona

open access: yesFrontiers in Public Health, 2021
Individuals living in congregate settings, including those in group homes, have been disproportionately impacted by COVID-19 and may be at increased risk of exposure or infection due to underlying illness.
Hayley D. Yaglom   +10 more
doaj   +1 more source

Image and graph convolution networks improve microbiome-based machine learning accuracy [PDF]

open access: yesarXiv, 2022
The human gut microbiome is associated with a large number of disease etiologies. As such, it is a natural candidate for machine learning based biomarker development for multiple diseases and conditions. The microbiome is often analyzed using 16S rRNA gene sequencing.
arxiv  

Short‐Chain Fatty Acids Modulate Anti‐ROR1 CAR T‐Cell Function and Exhaustion in an Intestinal Adenocarcinoma‐on‐Chip Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Short‐chain fatty acids modulate anti‐ROR1 chimeric antigen receptor (CAR) T‐cell function in an intestinal adenocarcinoma‐on‐chip model. Butyrate and propionate reduce cytotoxicity, cytokine release, and infiltration by inducing a regulatory T‐cell phenotype and T‐cell exhaustion via histone deacetylase inhibition.
Valentin D. Wegner   +5 more
wiley   +1 more source

Gut microbiota wellbeing index predicts overall health in a cohort of 1000 infants

open access: yesNature Communications
The human gut microbiota is central in regulating all facets of host physiology, and in early life it is thought to influence the host’s immune system and metabolism, affecting long-term health.
Brandon Hickman   +6 more
doaj   +1 more source

Bacteriophages fEV-1 and fD1 Infect Yersinia pestis

open access: yesViruses, 2021
Bacteriophages vB_YpeM_fEV-1 (fEV-1) and vB_YpeM_fD1 (fD1) were isolated from incoming sewage water samples in Turku, Finland, using Yersinia pestis strains EV76 and KIM D27 as enrichment hosts, respectively.
Mikael Skurnik   +6 more
doaj   +1 more source

A Bio‐Inspired Perspective on Materials Sustainability

open access: yesAdvanced Materials, EarlyView.
This perspective discusses natural materials as inspiration for sustainable engineering designs and the processing of materials. First, circularity, longevity, parsimony, and activity are presented as essential material paradigms. The perspective then uses many examples of natural and technical materials to introduce principles such as oligo ...
Wolfgang Wagermaier   +2 more
wiley   +1 more source

Ethanolamine enhances adhesion, promotes microcompartment formation, and modulates gene expression in Levilactobacillus brevis ATCC 14869

open access: yesGut Microbes
Ethanolamine is an abundant compound in the gastrointestinal tract and a valuable source of carbon and nitrogen for pathogenic bacteria harboring ethanolamine utilization (eut) genes.
Polycronis P. Akouris   +6 more
doaj   +1 more source

Human Limits in Machine Learning: Prediction of Plant Phenotypes Using Soil Microbiome Data [PDF]

open access: yesarXiv, 2023
The preservation of soil health is a critical challenge in the 21st century due to its significant impact on agriculture, human health, and biodiversity. We provide the first deep investigation of the predictive potential of machine learning models to understand the connections between soil and biological phenotypes.
arxiv  

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