Results 171 to 180 of about 515,553 (312)

Workflow for the Isolation and Characterisation of Human Milk Extracellular Vesicles (HMEVs) and Their Inflammatory Biomarker Profile. [PDF]

J Extracell Biol
Moreno-Casillas JL, Ripoll-Seguer L, Ten-Doménech I, Gómez-Ferrer M, Sepúlveda P, Albiach-Delgado A, Sanjuan-Herráez JD, Gormaz M, Pérez-Guaita D, Lendl B, Cernada M, Quintás G, Kuligowski J.   +12 more
europepmc   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Human Milk Macronutrient and Energy Contents Are Associated with Maternal and Infant Factors: A Cross-Sectional Analysis of Data from the Japanese Human Milk Study Cohort. [PDF]

Curr Dev Nutr
Nojiri K, Nomura K, Takahashi T, Tsujimori Y, Yasueda T, Higurashi S.   +5 more
europepmc   +1 more source

Structures of Neutral O-Linked Polylactosaminoglycans on Human Skim Milk Mucins

, 1989
F G Hanisch, G. Uhlenbruck, Jasna Peter‐Katalinić, Heinz Egge, J. Da̧browski, Ursula Dąbrowski   +5 more
openalex   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Human milk donation in Australia: a qualitative study of donors and potential donors. [PDF]

Int Breastfeed J
Newman C, Edwards AR, Hyde MK, Clifford V, Klein LD, Masser BM.   +5 more
europepmc   +1 more source

Characterising the Human Milk Microbiota of Indian Mothers: Prospects for Probiotic Discoveries and Antimicrobial Peptides [PDF]

H Anil, Somashekhar Nimbalkar, Chaitanya G. Joshi, Anju Kunjadiya, A. M. Patel, Reshma Pujara, Krutarth Raval, Satyamitra Shekh, Priyanka Dalwadi, Dipen Patel   +9 more
openalex   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Genomic characterization of normal and aberrant human milk production. [PDF]

Sci Adv
Golan Y, Nyquist SK, Liu Z, Ennis D, Zhao J, Blair E, Khan AR, Prahl M, Gaw SL, Yassour M, Engelhardt BE, Flaherman VJ, Ahituv N.   +12 more
europepmc   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source