Functional effects of human milk oligosaccharides (HMOs)
Gut Microbes, 2023 Human milk oligosaccharides (HMOs) are the third most important solid component in human milk and act in tandem with other bioactive components. Individual HMO levels and distribution vary greatly between mothers by multiple variables, such as secretor ...
Meltem Dinleyici +3 more
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Creation of a milk oligosaccharide database, MilkOligoDB, reveals common structural motifs and extensive diversity across mammals [PDF]
Scientific Reports, 2023 The carbohydrate fraction of most mammalian milks contains a variety of oligosaccharides that encompass a range of structures and monosaccharide compositions.
Sierra D. Durham +4 more
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Glycosyltransferases: glycoengineers in human milk oligosaccharide synthesis and manufacturing [PDF]
Frontiers in Molecular BiosciencesHuman milk oligosaccharides (HMOs) are a diverse group of complex carbohydrates that play crucial roles in infant health, promoting a beneficial gut microbiota, modulating immune responses, and protecting against pathogens.
Alanna S. Slater +4 more
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Human milk oligosaccharide mediates mutualism between Escherichia coli and Bifidobacterium bifidum [PDF]
Nature CommunicationsInfant gut microbiota development involves frequent colonization by Enterobacteriaceae, particularly Escherichia coli, yet their ecological role in healthy infants is unclear. Here, we analyse longitudinal stool samples from healthy, term-born, breastfed
David Seki +11 more
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Residential green environments are associated with human milk oligosaccharide diversity and composition [PDF]
Scientific Reports, 2023 Increased exposure to greener environments has been suggested to lead to health benefits in children, but the associated mechanisms in early life, particularly via biological mediators such as altered maternal milk composition, remain largely unexplored.
Mirkka Lahdenperä +10 more
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Role of human milk oligosaccharide metabolizing bacteria in the development of atopic dermatitis/eczema [PDF]
Frontiers in Pediatrics, 2023 Despite affecting up to 20% of infants in the United States, there is no cure for atopic dermatitis (AD), also known as eczema. Atopy usually manifests during the first six months of an infant's life and is one predictor of later allergic health problems.
Trisha Rahman +4 more
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Infant formulas with synthetic oligosaccharides and respective marketing practices
Molecular and Cellular Pediatrics, 2022 Human milk contains more than 150 different oligosaccharides, which together are among to the quantitatively predominant solid components of breast milk.
Christoph Bührer +8 more
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Unusual free oligosaccharides in human bovine and caprine milk
Scientific Reports, 2022 Free oligosaccharides are abundant macronutrients in milk and involved in prebiotic functions and antiadhesive binding of viruses and pathogenic bacteria to colonocytes.
Wei-Chien Weng +8 more
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Potential of lacto-N-biose I as a prebiotic for infant health: A review
Communications in Science and Technology, 2021 Prebiotic is one alternative in the prevention of disease in infants. Generally, it is available as oligosaccharide which may occur naturally, but can also be added as a dietary supplement for food, beverage or formula.
Warsono El Kiyat +3 more
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Chemoenzymatic Synthesis of Asymmetrically Branched Human Milk Oligosaccharide Lacto-N-Hexaose
Frontiers in Chemistry, 2022 We herein reported the first chemoenzymatic synthesis of lacto-N-hexaose (LNH) by combining chemical carbohydrate synthesis with a selectively enzymatic glycosylation strategy.
Kai-Eng Ooi +5 more
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