Results 11 to 20 of about 8,216,754 (227)

Human norovirus inhibition by a human milk oligosaccharide

Virology, 2017
Human noroviruses are the leading cause of outbreaks of acute gastroenteritis. Norovirus interactions with histo-blood group antigens (HBGAs) are known to be important for an infection. In this study, we identified the HBGA binding pocket for an emerging GII genotype 17 (GII.17) variant using X-ray crystallography.
Koromyslova, A, Tripathi, S, Morozov, V, Schroten, H, Hansman, GS   +4 more
openaire   +4 more sources

Characteristics of Oligosaccharide Composition in Chinese Human Milk [PDF]

Shipin Kexue
To analyze the impact of different regions, lactation times, and blood group genotypes on the oligosaccharide composition of healthy lactating mothers’ breast milk from representative regions of China, and to explore the compositional characteristics of ...
MI Lijuan, YAN Jingyu, GUO Shanshan, JIA Ni, PANG Jinzhu
doaj   +3 more sources

Seal milk oligosaccharides rival human milk complexity and exhibit functional dynamics during lactation [PDF]

Nature Communications
Milk oligosaccharides are crucial for neonatal development and health in mammals. Yet most milk research focuses on humans, or on domesticated mammals that are poor in milk oligosaccharide complexity.
Chunsheng Jin, Jon Lundstrøm, Carmen R. Cori, Shih-Yun Guu, Alexander R. Bennett, Mirjam Dannborg, Patrick P. Pomeroy, Malcolm W. Kennedy, Johan Bengtsson-Palme, Rachel Hevey, Kay-Hooi Khoo, Daniel Bojar   +11 more
doaj   +2 more sources

Human milk oligosaccharides as prebiotics

Pediatrics & Neonatology, 2023
Based on its richness in immune-related components such as human milk, human milk oligosaccharides (HMOs), milk proteins, and lipids, breast milk can be considered the first functional food that humans encounter in their lifetime. According to WHO recommendations breast milk has to be the only food in an infant's diet in the first six months of age ...
Gozde Okburan, Serap Kızıler
openaire   +5 more sources

Human milk oligosaccharide profiles and food sensitization among infants in the CHILD Study [PDF]

, 2022
Human milk oligosaccharide profiles and food sensitization among infants in the CHILD StudyCanadian Institutes of Health Research The Allergy, Genes and Environment (AllerGen) Network of Centres of Excellence The International Society for Research in ...
Subbarao, Padmaja, Becker, Allan B, Azad, Meghan, Miliku, Kozeta, Mandhane, Piush J., Sharma, A.K, Lefebvre, D.L., Bode, Lars, Robertson, B, Sears, Malcolm R, Turvey, Stuart E., the CHILD Study Investigators, /   +11 more
core   +1 more source

Unusual milk oligosaccharides and the biosynthetic pathways [PDF]

, 2022
Free oligosaccharides are abundant macronutrients in milk and involved in prebiotic functions and antiadhesive binding of pathogenic bacteria to colonocytes.
Wei-Chien , Weng, Hun-En, Liao, Hsu-Chen, Hsu, Chia-Yen, Liew, Shih-Pei, Huang, Veeranjaneyulu, Gannedi, Shang-Ting, Tsai, Shang-Cheng, Hung, Chi-Kung, Ni   +8 more
core   +1 more source

Human milk oligosaccharide 2'-fucosyllactose guards norovirus histo-blood group antigen co-factor binding site. [PDF]

J Virol
Histo-blood group antigens (HBGAs) are critical polymorphic glycan co-factors required for most norovirus infections (1, 2). However, human milk oligosaccharide (HMO) 2’-fucosyllactose (2’-FL), a component of human breast milk and made up of related ...
Rudd PA, Kher G, Tame JRH, Irie H, Haselhorst T, von Itzstein M, Pancera M, Hansman GS.   +7 more
europepmc   +2 more sources

Immunological Effects of Human Milk Oligosaccharides [PDF]

Frontiers in Pediatrics, 2018
Human milk oligosaccharides (HMOs) comprise a group of structurally complex, unconjugated glycans that are highly abundant in human milk. HMOs are minimally digested in the gastrointestinal tract and reach the colon intact, where they shape the microbiota. A small fraction of HMOs is absorbed, reaches the systemic circulation, and is excreted in urine.
Vassilis Triantis, Lars Bode, R. J. Joost van Neerven, R. J. Joost van Neerven   +3 more
openaire   +4 more sources

Short-Term Effects of Human versus Bovine Sialylated Milk Oligosaccharide Microinjection on Zebrafish Larvae Survival, Locomotor Behavior and Gene Expression [PDF]

, 2023
Milk oligosaccharides are a complex class of carbohydrates that act as bioactive factors in numerous defensive and physiological functions, including brain development.
Fronte, Baldassare, Doccini, Stefano, Naef, Valentina, Damiani, Devid, Marchese, Maria, Stefano Doccini, Filippo M. Santorelli, Ogi, Asahi, Jingyu Yan, Asahi Ogi, Licitra, Rosario, Yan, Jingyu, Maria Marchese, Valentina Naef, Santorelli, Filippo M, Rosario Licitra, Devid Damiani, Baldassare Fronte, Santorelli, Filippo M.   +18 more
core   +1 more source

Tailoring Human Milk Oligosaccharides to Prevent Necrotising Enterocolitis Among Preterm Infants

Frontiers in Nutrition, 2021
Necrotising enterocolitis (NEC) is a devastating disease affecting preterm infants, with little improvement in mortality rates and treatment strategies in the last 30 years.
Safiyyah Abbas, Amy K. Keir, Amy K. Keir, Amy K. Keir, Amy K. Keir, Maria Makrides, Maria Makrides, Laura D. Klein, Luke E. Grzeskowiak, Luke E. Grzeskowiak, Andrew J. McPhee, Alice R. Rumbold, Alice R. Rumbold, Alice R. Rumbold   +13 more
doaj   +1 more source