Results 51 to 60 of about 8,216,754 (227)
Efforts to emulate human milk oligosaccharides [PDF]
British Journal of Nutrition, 2007 Research on human milk oligosaccharides (HMO) began with the characterisation of their chemical structures and is now focused on the elucidation of their biological roles. Previously, biological effects could only be investigated with fractions or structures isolated from breast milk; consequently, clinical observations were limited to comparisons ...
Rosa María, Espinosa +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Advanced Science, EarlyView.Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu +10 more
wiley +1 more source
Evaluation of Organic Environmental Pollutants Detected in Human Milk [PDF]
, 2009 Human milk is an important food source for infant because it contains a large number of nutritional substances, growth and immune factors. However, human milk may be contaminated with environmental pollutants when mothers are exposed to these pollutants.
Kuroda, Naotaka, Kishikawa, Naoya
core +1 more source
Пищевые системы, 2023 Functional oligosaccharides include various groups of carbohydrates with the biological activity — an ability to modulate gut microbiota due to the prebiotic, anti-adhesive and anti-inflammatory activities.
E. A. Yurova, N. V. Ananyeva
doaj +1 more source
Advanced Science, EarlyView.This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang +10 more
wiley +1 more source
, 2022 We herein reported the first chemoenzymatic synthesis of lacto-N-hexaose (LNH) by combining chemical carbohydrate synthesis with a selectively enzymatic glycosylation strategy.
Xiu-Wen Zhang (7037090) +4 more
core +1 more source
Imidazolium-labeled glycosides as probes to harness glycosyltransferase activity in human breast milk [PDF]
, 2017 Imidazolium-labeled (ITag-) glycosides have been used to harness the glycosyltransferase activity directly from human breast milk (HBM). The technology is exemplified in the synthesis of biologically relevant oligosaccharide analogs, ITag-LacNAc, ITag ...
M. C. Galan, I. Sittel
core +2 more sources
Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope
Animal Research and One Health, EarlyView.FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad +7 more
wiley +1 more source
Human milk variation is shaped by maternal genetics and impacts the infant gut microbiome
Cell GenomicsSummary: Human milk is a complex mix of nutritional and bioactive components that provide complete nourishment for the infant. However, we lack a systematic knowledge of the factors shaping milk composition and how milk variation influences infant health.
Kelsey E. Johnson +14 more
doaj +1 more source