Results 31 to 40 of about 7,482,097 (194)

Hepatic Pathology in Human Monocytic Ehrlichiosis: Ehrlichia chaffeensis Infection [PDF]

open access: yesAmerican Journal of Clinical Pathology, 2003
Ehrlichia chaffeensis causes human monocytic ehrlichiosis (HME) that usually includes fever, myalgias, and pancytopenia and, in 80% to 90% of patients, elevations in serum transaminase levels. Thus, the pathology of liver injury was studied in liver tissues from 7 patients with laboratory-confirmed HME.
Ann E, Sehdev, J Stephen, Dumler
openaire   +2 more sources

Glutathione Synthesis Regulated by CtrA Protects Ehrlichia chaffeensis From Host Cell Oxidative Stress

open access: yesFrontiers in Microbiology, 2022
Ehrlichia chaffeensis, a small Gram-negative obligatory intracellular bacterium, infects human monocytes or macrophages, and causes human monocytic ehrlichiosis, one of the most prevalent, life-threatening emerging zoonoses.
Jiaqi Yan   +11 more
doaj   +1 more source

Effect of storage on the nitro blue tetrazolium reduction test in dog blood samples

open access: yesVeterinary Clinical Pathology, Volume 52, Issue 4, Page 596-600, December 2023., 2023
Abstract Introduction The nitro blue tetrazolium (NBT) reduction test (NBTT) has been used for measuring the metabolic activity of phagocytes of mammals. Activated neutrophils transform NBT into formazan in the cytoplasm. The NBTT can detect the activation of neutrophils in peripheral blood and is used to assess neutrophil function in dogs.
Marta Baxarias, Laia Solano‐Gallego
wiley   +1 more source

Western Blot Analysis of Sera Reactive to Human Monocytic Ehrlichiosis and Human Granulocytic Ehrlichiosis Agents [PDF]

open access: yesJournal of Clinical Microbiology, 2001
ABSTRACT Laboratory diagnosis of human ehrlichioses is routinely made by an indirect immunofluorescence assay (IFA) using cultured ehrlichia-infected whole cells as antigen. Concern has been raised that incorrect diagnoses of human monocytic ehrlichiosis (HME) or human granulocytic ehrlichiosis (HGE) may be made on the basis of ...
ÜNVER, AHMET   +7 more
openaire   +3 more sources

Ehrlichiosis‐Associated Hemophagocytic Lymphohistiocytosis: A Case Series and Review of the Literature

open access: yesCase Reports in Hematology, Volume 2023, Issue 1, 2023., 2023
Background. Human monocytic ehrlichiosis (HME) is a potentially life‐threatening tick‐borne illness. HME‐associated hemophagocytic lymphohistiocytosis (HLH) is a rare entity with a paucity of published literature regarding treatment and outcome. We present the clinical features, treatment, and outcomes of 4 patients at our institutions with HME ...
Kassem Hammoud   +4 more
wiley   +1 more source

Non-Canonical Inflammasome Pathway: The Role of Cell Death and Inflammation in Ehrlichiosis

open access: yesCells, 2023
Activating inflammatory caspases and releasing pro-inflammatory mediators are two essential functions of inflammasomes which are triggered in response to pathogen-associated molecular patterns (PAMPs) or danger-associated molecular patterns (DAMPs).
Aditya Kumar Sharma, Nahed Ismail
doaj   +1 more source

Features of human monocytic ehrlichiosis laboratory diagnostics

open access: yesPerm Medical Journal, 2022
Objective. Using the data obtained in Perm Region as an example, to identify the effectiveness of polymerase chain reaction (PCR) for the diagnosis of Human Monocytic Ehrlichiosis (HME) at different periods from the onset of the disease, and to determine the role of HME in the structure of infections transmitted by ixodic ticks using PCR and enzyme ...
V. Yu. Teterin   +6 more
openaire   +1 more source

Oxidative Stress Evaluation in Dogs Affected with Canine Monocytic Ehrlichiosis

open access: yes, 2022
The study aimed to evaluate the concentration of reactive oxidative metabolites (R-OOHs), the antioxidant barrier (OXY), and the ratio between R-OOHs and OXY (OSi) and thiol groups of plasma compounds (SHp) in in canine monocytic ehrlichiosis.
Michela Pugliese   +4 more
core   +1 more source

Sudden Sensorineural Hearing Loss in Human Monocytic Ehrlichiosis [PDF]

open access: yesEar, Nose & Throat Journal, 2017
The hallmarks of symptomatic human monocytic ehrlichiosis (HME) include fever, headache, myalgia, nausea, malaise, transaminitis, and blood cell abnormalities. Previous case reports have described isolated cranial nerve palsies in infected patients but not hearing loss. We describe the onset of sudden sensorineural hearing loss in 2 patients with HME—a
Vidur, Bhalla   +2 more
openaire   +2 more sources

CtrA activates the expression of glutathione S-transferase conferring oxidative stress resistance to Ehrlichia chaffeensis

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Ehrlichia chaffeensis, the causative agent of human monocytic ehrlichiosis (HME), is a Gram-negative obligatory intracellular bacterium, which infects and multiplies in human monocytes and macrophages.
Qi’an Liang   +8 more
doaj   +1 more source

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