Results 71 to 80 of about 8,048,182 (359)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Anarchist-Socialist Praxis and Embodied Human Nature
Eidos. A Journal for Philosophy of CultureThe idea of human nature can be wielded to justify exploitation and domination, but drawing on the work of Noam Chomsky, Murray Bookchin and others, I argue consideration of our embodied nature can help humans thrive.
James Anderson
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A Needs-Based Partial Theory of Human Injustice: Oppression, Dehumanization, Exploitation, and Systematic Inequality in Opportunities to Address Human Needs [PDF]
, 2019 The article presents an original needs-based partial theory of human injustice and shows its relationship to existing theories of human need and human liberation.
Dover, Michael Alan
core +3 more sources
, 2020 Nature is made up of various living and non-living things which is related to plants, animals and other features such as mountains, deserts and seas. They are connected and some of the relationships between members are direct and obvious and ecosystem ...
Jais, Noor Maisara +1 more
core
Commodities and cognition [PDF]
, 2014 A commentary on "An enquiry concerning the nature of conceptual categories: a case-study on the social dimension of human cognition", by John Stewart (2014)in 'Frontiers in Psychology', Vol ...
Loader, Paul
core +2 more sources
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
EXPLAINING AND VALUING: AN EXCHANGE BETWEEN THEOLOGY AND THE HUMAN SCIENCES
Zygon, 1995 . A comparison of E.O. Wilson's On Human Nature and Abraham Heschel's Who Is Man? introduces a discussion of how descriptions and explanations of the human are related to valuations of the human.
doaj +2 more sources
Serviço Social em Revista, 2010 The concept of solidarity inhabits the collective unconscious and is usually related to something consensual, linked to the most basic values of mankind, but to expand that understanding leads to more complex views.
Luis Miguel dos Santos Luzio +1 more
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source