Results 41 to 50 of about 232,126 (306)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The role and mechanism of human papillomavirus in urinary system tumors

Journal of International Medical Research
Based on the level of carcinogenic risk, human papillomavirus can be categorized into high-risk and low-risk types. High-risk human papillomavirus (such as human papillomavirus 16 and human papillomavirus 18) induces the inactivation of tumor suppressor ...
Hongxia Huang, Shubing Feng, Yuanhang Liu   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Detection of human papillomavirus in oral warts using in situ hybridization [PDF]

RGO: Revista Gaúcha de Odontologia, 2008
Objective: The human papillomavirus is a group of DNA epitheliotrophic viruses associated with the etiology of benign and malignant oral warts. More than 100 types have been identified and among them, 24 have been found into the oral cavity.
Suzana Orsini Machado de Sousa, Oliver Guilherme da Silva, Péricles Martim Reche, Renata Rodrigues Acay, Cristhiane Almeida Leite   +4 more
doaj  

Bacterial vaginosis, cervical Human Papillomavirus infection and cervical cytological abnormalities in adult women in Central Brazil: A cross-sectional study

DST, 2022
Introduction: Bacterial vaginosis is the most common cause of vaginal discharge and occurs when there is an imbalance in the vaginal microbiota, predominantly composed of Lactobacillus spp.
Bruno César Teodoro Martins, Kélvia Cristina de Camargo, Jamila Pimentel Lima, Jéssica Enocêncio Porto Ramos, Camila Lemes de Souza, Sílvia Helena Rabelo dos Santos, Vera Aparecida Saddi, Rosane Ribeiro Figueiredo Alves   +7 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Prevalence of cervical disease at age 20 after immunisation with bivalent HPV vaccine at age 12-13 in Scotland: retrospective population study [PDF]

, 2019
The manuscript was reviewed by Jo’s Trust, which supports the conclusions. It made the following statement: We think (it has) massive implications for the screening programme, vaccine and also impact on diagnoses in the future.
Cruickshank, Margaret, Cuschieri, Kate, Kavanagh, Kim, Palmer, Tim, Pollock, Kevin G., Robertson, Chris, Wallace, Lynn   +6 more
core   +4 more sources

Implementation costs of a multi-component program to increase human papillomavirus (HPV) vaccination in a network of pediatric clinics [PDF]

, 2020
Introduction: HPV vaccination is both a clinically and cost-effective way to prevent HPV-related cancers. Increased focus on preventing HPV infection and HPV-related cancers has motivated development of strategies to increase adolescent vaccination rates.
Eska, Jarrod S, Fernandez, Maria E, Healy, C Mary, Lairson, David R, Savas, Lara S., Shegog, Ross, Spinner, Stanley W, MD, Vernon, Sally W.   +7 more
core   +2 more sources

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Regulation of HPV transcription

Clinics, 2018
Human papillomavirus infection is associated with the development of malignant and benign neoplasms. Approximately 40 viral types can infect the anogenital mucosa and are categorized into high- and low-risk oncogenic human papillomavirus, depending on ...
Aline Lopes Ribeiro, Amanda Schiersner Caodaglio, Laura Sichero   +2 more
doaj   +1 more source