Results 61 to 70 of about 137,758 (217)

HPV Genotype Distribution in Cervical Cancer and High‐Grade Lesions in Norway, and Early Vaccine Impact

International Journal of Cancer, EarlyView.
ABSTRACT All cases of invasive cervical cancer (ICC) and subsets of high‐grade cervical intraepithelial neoplasia grade 2 or 3 (CIN2/3) and adenocarcinoma in situ (AIS) in Norway are tested for 37 human papillomavirus (HPV) genotypes, within a mandatory national surveillance system.
Terese Bekkevold, Ida Laake, Berit Feiring, Kristiane Søreng, Gro Kummeneje Presthus, Glenny Cecilie Alfsen, Irene Kraus Christiansen, Mona Hansen, Hanne Kristiansen, Eirik Olsen, Torstein Gjølgali Frengen, Emily A. Burger, Christine Genieve Monceyron Jonassen, Lill Trogstad   +13 more
wiley   +1 more source

Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer

International Journal of Cancer, EarlyView.
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue, Daniele Carchidi, Philipp Schmucker, Roland Seiler, Bernhard Kiss, Catarina Macedo‐Silva, Marianna Kruithof‐de Julio   +6 more
wiley   +1 more source

Controlled Trial of Cervical Cancer Screening Frequency Among Human Papillomavirus Vaccinated Women II: Cervical Pre‐Cancer End‐Points by Specific Non‐Vaccine HPV Types

International Journal of Cancer, EarlyView.
ABSTRACT We conducted a controlled trial among 5626 early adolescent women vaccinated in 2007–2009 against human papillomavirus (HPV) types 16/18 to evaluate the impact of high‐intensity versus low‐intensity cervical screening, respectively at ages 22/25/28 and 28 years with squamous‐cell intraepithelial lesions (SILs) as the end‐point.
Matti Lehtinen, Mònica Ortega Llobet, Tiina Eriksson, Iacopo Baussano, Miriam Elfström, Mehran Ghaderi, Penelope Gray, Katja Harjula, Kaisa Heikkilä, Mari Hokkanen, Saara Kares, Camilla Lagheden, Pekka Nieminen, Anna Söderlund‐Strand, Joakim Dillner, Ville N. Pimenoff   +15 more
wiley   +1 more source

Cancer in Seychelles: A Population‐Based Study on Incidence, Trends and Stage at Diagnosis (2005–2024)

International Journal of Cancer, EarlyView.
ABSTRACT Seychelles, the smallest country in Africa but with the highest GDP per capita, has experienced rapid socioeconomic development. We analysed 20‐year cancer incidence trends (2005–2024) using data from the Seychelles National Cancer Registry (SNCR).
Anne Finesse, Jolene Mondon, Emelyn Shroff, Jude Gedeon, Meggy Louange, Donald Maxwell Parkin   +5 more
wiley   +1 more source

Invasive Cervical Cancers After an HPV‐Negative Test: Insights From HPV Testing Histories

International Journal of Cancer, EarlyView.
ABSTRACT Human papillomavirus (HPV) testing is the primary method for cervical screening, and a negative HPV test is associated with a very low subsequent risk of invasive cancer. Nevertheless, some cervical cancers are diagnosed following an HPV‐negative test.
Sadaf Sakina Hassan, Sara Nordqvist Kleppe, Nijin Asinger, Jiangrong Wang, Joakim Dillner, Laila Sara Arroyo Mühr   +5 more
wiley   +1 more source

Comparison of HPV Antibodies Measured Prior to Diagnosis of Anal, Cervical, Oropharyngeal, Penile and Vaginal Cancers in the HPV Cancer Cohort Consortium

International Journal of Cancer, EarlyView.
ABSTRACT Antibodies against HPV proteins can provide pre‐diagnostic information about cancer development. We described the prevalence of antibodies to proteins of oncogenic HPV types prior to diagnosis of HPV‐related cancers. We analysed pre‐diagnostic blood from 1700 participants with incident HPV‐related cancers (anal = 387, cervical = 274 ...
Justina Ucheojor Onwuka, Marie‐Pierre Nobels, Aimée R. Kreimer, Lea Schroeder, Aida Ferreiro‐Iglesias, Ilir Agalliu, Demetrius Albanes, Qiuyin Cai, Gypsyamber D'Souza, Neal D. Freedman, Graham G. Giles, Allan Hildesheim, Wen‐Yi Huang, Kristian Hveem, Hilde Langseth, Roger L. Milne, Eivind Ness‐Jensen, Nicolas F. Schlecht, Lesley F. Tinker, Giske Ursin, Kala Visvanathan, Sylvia Wassertheil‐Smoller, Stephanie J. Weinstein, Wei Zheng, Mari Nygard, Mattias Johansson, Tim Waterboer, Gary M. Clifford, Hilary A. Robbins   +28 more
wiley   +1 more source

Validation of the WID‐CIN Methylation Test for Detection of Cervical Intraepithelial Neoplasia Grade 3 or Worse in an Independent Cohort

International Journal of Cancer, EarlyView.
ABSTRACT Many cervical screening programmes rely on cytology for triage of high‐risk human papillomavirus (hrHPV) positive women. However, cytological triage has variable and often limited sensitivity, and its availability can be restricted in resource‐poor settings.
Laura Burney Ellis, Sarah J. Bowden, Jack Tighe, Muhammad Habiburrahman, Katerina‐Vanessa Savva, Maria Paraskevaidi, Maria Nasioutziki, Chris J. Peters, James M. Flanagan, Maria Kyrgiou   +9 more
wiley   +1 more source

Yield of endocervical curettage in detecting cervical intraepithelial neoplasia grade 2 or higher during colposcopy: A prospective, cross‐sectional study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 105-111, April 2025.
Abstract Objective This study assessed the prevalence and factors associated with detecting cervical intraepithelial neoplasia grade 2 or higher (CIN2+) via endocervical curettage (ECC) during colposcopy. Methods Between December 2020 and September 2023, a prospective, cross‐sectional study involving women with abnormal cervical cancer screening ...
Nida Jareemit, Lalita Theerarojanapong, Natthawadee Laokulrath, Vuthinun Achariyapota, Khemanat Khemworapong, Sompop Kuljarasnont, Pornporm Ittiamornlert, Vitcha Poonyakanok, Perapong Inthasorn   +8 more
wiley   +1 more source

Chlamydia trachomatis as a probable cofactor in human papillomavirus infection in aboriginal women from northeastern Argentina

Brazilian Journal of Infectious Diseases, 2011
Objectives: High-risk types of human papillomavirus (HPV) are strongly associated with cervical cancer (CC), and Chlamydia trachomatis (CT), the most frequent sexually transmitted bacterial infection (STBI) worldwide, seems to be a risk factor for HPV ...
Gerardo Daniel Deluca, PhD, MSc, Jorge Basiletti, Eduardo Schelover, MD, Nicolás Díaz Vásquez, MD, José Mario Alonso, PhD, Héctor Marcelo Marín, Raúl Horacio Lucero, María Alejandra Picconi, PhD   +7 more
doaj   +1 more source

Lymphovascular space involvement as a prognostic factor for survival outcomes in vulvar cancer: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Lymphovascular space involvement (LVSI) is a significant prognostic factor of survival outcomes in gynecologic oncology. Synthetic studies on vulvar cancer are lacking as well as clear consensus about the importance of LSVI in vulvar cancer.
Vasilios Pergialiotis, Maria Fanaki, Michail Panagiotopoulos, Vasilios Lygizos, Dimitrios Efthimios Vlachos, Nikolaos Thomakos, Dimitrios Haidopoulos   +6 more
wiley   +1 more source