Results 171 to 180 of about 55,515 (211)

Human infection by a bovine strain of parainfluenza virus type 3

Journal of Medical Virology, 1980
AbstractEtiological relationship between a bovine strain of parainfluenza virus type 3 and pneumonia in a child is suggested. Haemagglutination inhibition tests have clearly demonstrated that specific antibodies against the bovine virus were present in the patient's serum. The significance of this finding in relation to human infection is discussed.
A Avram, S Yatziv
exaly   +3 more sources

Proteins associated with human parainfluenza virus type 3

Journal of Virology, 1985
The polypeptides associated with human parainfluenza virus type 3 were identified. Five proteins were present in detergent- and salt-resistant viral cores. Of these, three proteins designated NP0, NP1, and NP2 of 68,000, 58,000, and 52,000 daltons, respectively, were stably associated with 50S RNA in CsCl gradient-purified nucleocapsids. The amounts of
R C, Jambou, N, Elango, S, Venkatesan
openaire   +2 more sources

Role of Heparan Sulfate in Human Parainfluenza Virus Type 3 Infection

Virology, 2002
Our current studies have demonstrated that human parainfluenza virus type 3 (HPIV-3) utilizes heparan sulfate (HS) for its efficient cellular entry. HPIV-3 interacted with HS-agarose in vitro and the cellular entry and infection of HPIV-3 were reduced following (a) infection of human epithelial lung A549 cells with HPIV-3 pre-incubated with soluble HS;
Santanu Bose, Amiya K Banerjee
exaly   +3 more sources

Inoculation of Human Volunteers with Parainfluenza Virus Type 3

JAMA, 1961
In an attempt to see whether parainfluenza virus type 3 would produce illness in adults, 28 adult volunteer subjects were inoculated with either the virus or a sterile salt solution. Twelve of the 17 volunteers inoculated with the virus, and none of the 11 who received the placebo inoculum, developed laboratory evidence of infection with parainfluenza ...
A Z, KAPIKIAN, R M, CHANOCK, T E, REICHELDERFER, T G, WARD, R J, HUEBNER, J A, BELL   +5 more
openaire   +2 more sources

Defective interfering particles of human parainfluenza virus 3

Virology, 1987
A cyclic pattern of virus production was observed when human parainfluenza virus 3 (HPIV3) was serially passaged nine times in LLC-MK2 cells. Viruses produced from serial passages 8 and 9 interfered with the replication of standard HPIV3. Three subgenomic RNA species (DI-1, DI-2, and DI-3) and virus genomic RNA were detected in the progeny virions ...
D G, Murphy, K, Dimock, C Y, Kang
openaire   +2 more sources

The Catalytic Mechanism of Human Parainfluenza Virus Type 3 Haemagglutinin‐Neuraminidase Revealed

Angewandte Chemie - International Edition, 2015
AbstractHuman parainfluenza virus type 3 (hPIV‐3) is one of the leading causes for lower respiratory tract disease in children, with neither an approved antiviral drug nor vaccine available to date. Understanding the catalytic mechanism of human parainfluenza virus haemagglutinin‐neuraminidase (HN) protein is key to the design of specific inhibitors ...
Larissa Dirr, Ibrahim M El-Deeb, Patrice Guillon   +2 more
exaly   +5 more sources