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Characterization of human parainfluenza virus-3 circulating in Israel, 2012-2015.
Journal of Clinical Virology, 2018BACKGROUND Human parainfluenza virus 3 (hPIV-3) causes respiratory tract infection. OBJECTIVES The objective of this study was to describe the epidemiology of hPIV-3 infection among hospitalized patients and characterize the circulating strains ...
I. Jornist +12 more
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The Catalytic Mechanism of Human Parainfluenza Virus Type 3 Haemagglutinin‐Neuraminidase Revealed
Angewandte Chemie, 2015AbstractHuman parainfluenza virus type 3 (hPIV‐3) is one of the leading causes for lower respiratory tract disease in children, with neither an approved antiviral drug nor vaccine available to date. Understanding the catalytic mechanism of human parainfluenza virus haemagglutinin‐neuraminidase (HN) protein is key to the design of specific inhibitors ...
Dirr, Larissa +5 more
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Defective interfering particles of human parainfluenza virus 3.
Virology, 1987A cyclic pattern of virus production was observed when human parainfluenza virus 3 (HPIV3) was serially passaged nine times in LLC-MK2 cells. Viruses produced from serial passages 8 and 9 interfered with the replication of standard HPIV3. Three subgenomic RNA species (DI-1, DI-2, and DI-3) and virus genomic RNA were detected in the progeny virions ...
D. Murphy, K. Dimock, C. Kang
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Evolution of the fusion protein gene of human parainfluenza virus 3.
Virus Research, 1992The nucleotide sequences of the fusion (F) gene of 15 clinical strains of human parainfluenza virus 3 (HPIV3) isolated between 1959 and 1987 were compared with the F gene sequence of the prototype strain, Wash/47885/57. Nucleotide sequence diversity was greatest in the noncoding regions of the F gene; however, regions believed to function as ...
K. Prinoski +3 more
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Liver Enzyme Elevation Related to Human Parainfluenza Virus Type 3 Infection
Pediatric Infectious Disease Journal, 2022The human parainfluenza viruses are common causes of upper and lower respiratory tract infection; however, nonrespiratory infections with human parainfluenza viruses are rare, and there are no reports of pediatric cases of liver enzyme elevation. We present 2 pediatric patients who developed liver enzyme elevation related to human parainfluenza virus ...
Yoshimasa Kudo +5 more
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Human parainfluenza virus 3 : genetic diversity, virulence and antiviral susceptibility
, 2019Human parainfluenza 3 (HPIV3) is a member of the Paramyxoviridae, a single strain negative-sense non-segmented RNA virus in the order Mononegavirales. It is a respiratory pathogen with a broad spectrum of presentations for which there is currently neither a vaccine nor licensed treatment for HPIV3.
A. Smielewska
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Proteins associated with human parainfluenza virus type 3
Journal of Virology, 1985The polypeptides associated with human parainfluenza virus type 3 were identified. Five proteins were present in detergent- and salt-resistant viral cores. Of these, three proteins designated NP0, NP1, and NP2 of 68,000, 58,000, and 52,000 daltons, respectively, were stably associated with 50S RNA in CsCl gradient-purified nucleocapsids. The amounts of
R C, Jambou, N, Elango, S, Venkatesan
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Inoculation of Human Volunteers with Parainfluenza Virus Type 3
JAMA, 1961In an attempt to see whether parainfluenza virus type 3 would produce illness in adults, 28 adult volunteer subjects were inoculated with either the virus or a sterile salt solution. Twelve of the 17 volunteers inoculated with the virus, and none of the 11 who received the placebo inoculum, developed laboratory evidence of infection with parainfluenza ...
A Z, KAPIKIAN +5 more
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