Results 201 to 210 of about 159,014 (249)

Molecular Epidemiology of an Outbreak of Human Parainfluenza Virus 3 Among Oncology Patients.

Journal of Hospital Infection, 2019
A hospital outbreak of human parainfluenza virus type 3 in hematologic oncology patients is described in 12 patients over a 4-week period. Exposure histories and molecular analysis of HPIV-3 isolates suggests that both community acquired and nosocomially
Emily S. Bailey, Erica Lobaugh-Jin, Becky A. Smith, Christopher Sova, Joey Misuraca, N. Henshaw, G. Gray   +6 more
semanticscholar   +1 more source

Cloning and gene assignment of mRNAs of human parainfluenza virus 3.

Virology, 1985
Cytoplasmic poly(A)-containing RNA from parainfluenza virus 3-infected cells was used as template to construct a cDNA library that was cloned into the EcoRV site of the plasmid pMG5. The resulting clones were screened with [32P]-labeled cDNA probes made from infected and mock-infected cell mRNAs.
A. Sanchez, A. Banerjee
semanticscholar   +3 more sources

Functional chimeric HN glycoproteins derived from Newcastle disease virus and human parainfluenza virus-3.

Archives of virology. Supplementum, 1997
Newcastle disease virus (NDV) is primarily a respiratory tract pathogen of birds, particularly chickens, but it occasionally produces infection in man. Human parainfluenza virus type 3 (hPIV3) is a common respiratory pathogen, particularly in young children. These two viruses gain entry to host cells via direct fusion between the viral envelope and the
Ruitang Deng, A. Mirza, P. J. Mahon, R. M. Iorio   +3 more
semanticscholar   +3 more sources

Intracellular synthesis of human parainfluenza type 3 virus-specified polypeptides

Journal of Virology, 1985
The intracellular synthesis of human parainfluenza type 3 virus-specified polypeptides was examined by polyacrylamide gel electrophoresis of [35S]methionine-labeled cell extracts under reducing conditions. All of the virion structural proteins were detected in cell extracts, including: L, 180,000 molecular weight (180K); P, 83K; HN, 69K; NP, 66K; F0 ...
S L, Wechsler, D M, Lambert, M S, Galinski, M W, Pons   +3 more
openaire   +2 more sources

Human Parainfluenza Virus 3 Neuraminidase Activity Contributes to Dendritic Cell Maturation

Viral Immunology, 2005
Mechanisms of dendritic cells (DCs) immunomodulation by parainfluenza viruses have not been characterized. We analyzed whether the human parainfluenza 3 (HPF3) virus hemagglutinin-neuraminidase glycoprotein (HN) might influence DC maturation. HN possesses a receptor binding function and a neuraminidase or desialidating activity.
M. Horga, S. Macip, Ana C. Tuyama, M. Tan, G. L. Gusella   +4 more
semanticscholar   +4 more sources

Human infection by a bovine strain of parainfluenza virus type 3

Journal of Medical Virology, 1980
AbstractEtiological relationship between a bovine strain of parainfluenza virus type 3 and pneumonia in a child is suggested. Haemagglutination inhibition tests have clearly demonstrated that specific antibodies against the bovine virus were present in the patient's serum. The significance of this finding in relation to human infection is discussed.
Z, Ben-Ishai, V, Naftali, A, Avram, S, Yatziv   +3 more
openaire   +2 more sources

The human parainfluenza virus type 3 (HPIV 3) C protein inhibits viral transcription

Virus Research, 2004
The C protein of human parainfluenza virus type 3 (HPIV 3), like other paramyxovirus C proteins, is synthesized from an alternate open reading frame (ORF) encoded within the phosphoprotein (P) mRNA, in addition, to two other proteins, namely D and V, which arise from the same mRNA by a process of transcriptional editing.
Achut G, Malur, Michael A, Hoffman, Amiya K, Banerjee   +2 more
openaire   +2 more sources

ISGylation during Human Parainfluenza Virus Type 3 Infection

The Journal of Immunology
Abstract Human parainfluenza virus type 3 (HPIV3) causes lower respiratory illnesses such as pneumonia or bronchiolitis in infants, young children, and the immunocompromised. HPIV3 associated airway inflammatory diseases manifest as a result of host mediated exaggerated inflammatory response, though limited knowledge exists regarding ...
Lindsay Miller, Liyon Mehari, Michael Hoffman, Santanu Bose   +3 more
openaire   +1 more source

Regulation of human parainfluenza virus type 3 transcription.

2009
To elucidate the roles of the junctional elements in HPIV3 transcription, cDNAs were constructed containing CAT and luciferase reporter genes flanked by sequences representing the HPIV3 termini necessary for transcription, replication and packaging. Mutations to the gene end sequence abolished expression of the upstream and downstream genes.
openaire   +2 more sources

Lentivirus vector pseudotyped with human parainfluenza virus type 3 glycoproteins

Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology, 2003
Lentiviral vectors pseudotyped with the envelope glycoproteins of amphotropic murine leukemia virus and the G protein of vesicular stomatitis virus have been previously developed for use in human gene therapy trials. We report here the generation of infectious replication-defective HIV-1 particles pseudotyped with hemagglutinin-neuraminidase (HN) and ...
B. Grzybowski, S. Tong, R.W. Compans, J.M. Le Doux   +3 more
openaire   +1 more source