Results 61 to 70 of about 44,207 (161)

Role of Nucleolin in Human Parainfluenza Virus Type 3 Infection of Human Lung Epithelial Cells [PDF]

Journal of Virology, 2004
ABSTRACT Human parainfluenza virus type 3 (HPIV-3) is an airborne pathogen that infects human lung epithelial cells from the apical (luminal) plasma membrane domain. In the present study, we have identified cell surface-expressed nucleolin as a cellular cofactor required for the efficient cellular entry of HPIV-3 into human lung ...
Santanu, Bose, Mausumi, Basu, Amiya K, Banerjee   +2 more
openaire   +2 more sources

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, Volume 10, Issue 3, Page 199-218, June 2026.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Wheat germ cell-free system-based production of hemagglutinin-neuraminidase protein of human parainfluenza virus type 3: generation and characterization of monoclonal antibody

Frontiers in Microbiology, 2014
Human parainfluenza virus 3 (HPIV3) commonly causes respiratory disorders in infants and young children. Monoclonal antibodies (MAbs) have been produced to several components of HPIV3 and commercially available.
Satoko eMatsunaga, Shiho eKawakami, Akiko eOkayama, Hiroyuki eTsukagoshi, Ayumi eKudoh, Izumi eMatsuo, Yuki eMatsushima, Hideaki eShimizu, Nobuhiko eOkabe, Hisashi eHirano, Naoki eYamamoto, Hirokazu eKimura, Akihide eRyo   +12 more
doaj   +1 more source

Impact of RSV Preventive Strategies on Hospitalizations for Bronchiolitis in Infants

Pediatric Pulmonology, Volume 61, Issue 6, June 2026.
ABSTRACT Introduction Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and hospitalization in infants. Since 2023, France has implemented two preventive strategies aimed at reducing RSV burden: long‐acting monoclonal antibody nirsevimab and RSV vaccine for pregnant women, the latter becoming available from September 2024.
Marine Tarizzo, Julie Mesinèle, Blandine Prevost, Sophie Denamur, Elora Peulier‐Maitre, Loïc Guillot, Nadia Nathan, Harriet Corvol   +7 more
wiley   +1 more source

Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length

Molecules, 2017
A set of lipopeptides was recently reported for their broad-spectrum antiviral activity against viruses belonging to the Paramyxoviridae family, including human parainfluenza virus type 3 and Nipah virus. Among them, the peptide with a 24-unit PEG linker
Marcelo T. Augusto, Axel Hollmann, Matteo Porotto, Anne Moscona, Nuno C. Santos   +4 more
doaj   +1 more source

Impact of Respiratory Viral Codetections on RSV Disease Burden in Young Children in Primary Care

Influenza and Other Respiratory Viruses, Volume 20, Issue 6, June 2026.
ABSTRACT Background Young children with respiratory syncytial virus (RSV) often have viral coinfections. This study assessed the impact of respiratory viral codetections on RSV disease burden in children < 5 years and whether this varies by specific codetected viruses.
Levi Duijst, Valérie Sankatsing, Caterina Rizzo, Francesco Baglivo, Elizabeth Button, Marta Carballal Mariño, María Garcés Sánchez, Christine Hagemann, Simon de Lusignan, Oliver Martyn, Marc Raes, Daan Van Brusselen, Joanne Wildenbeest, Sarah Hak, Foekje Stelma, Jojanneke van Summeren, on behalf of the RSV ComNet network   +16 more
wiley   +1 more source

The Cotton Rat as an Experimental Model of Human Parainfluenza Virus Type 3 Disease

Experimental Lung Research, 1981
Intranasal or aerosol inoculation of cotton rats (Sigmodon hispidus) with human parainfluenza virus type 3 (P3) produces pulmonary changes which closely resemble human disease due to this agent. Active viral replication resulted in peak titers by day 2 of infection.
T F, Murphy, E J, Dubovi, W A, Clyde
openaire   +2 more sources

Antiviral activity of mycosynthesized silver nanoparticles against herpes simplex virus and human parainfluenza virus type 3

International Journal of Nanomedicine, 2013
Swapnil Gaikwad,1 Avinash Ingle,1 Aniket Gade,1 Mahendra Rai,1 Annarita Falanga,3 Novella Incoronato,2 Luigi Russo,2 Stefania Galdiero,3 Massimilano Galdiero2 1Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati, Maharashtra, India;
Gaikwad S, Ingle A, Gade A, Rai M, Falanga A, Incoronato N, Russo L, Galdiero S, Galdiero M   +8 more
doaj  

Heterogeneous Causes of Acute Respiratory Distress Syndrome Correlate With Distinct Peripheral Polyunsaturated Fatty Acid Metabolites

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Inflammatory insults, such as sepsis, pneumonia, aspiration, or trauma can trigger an inflammatory reaction leading to Acute Respiratory Distress Syndrome (ARDS). This study identified that different causes lead to differences in n−3 and n−6 polyunsaturated fatty acids (PUFAs) and their downstream oxylipins.
Laura A. Leuenberger, Joseph S. Bednash, Evangeline Schott, Carmen Mikacenic, Eric D. Morrell, Carson Richardson, Lynn A. Fussner, Jeffrey C. Horowitz, Rama K. Mallampalli, Saame Raza Shaikh, Robert M. Tighe, Kymberly M. Gowdy   +11 more
wiley   +1 more source

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1487-1492, May 2026.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart, Emiel Leegwater, Thomas H. Ottens, Emile F. Schippers, Erik B. Wilms, David M. Burger, Cees van Nieuwkoop, Liesbeth B. E. Bosma   +7 more
wiley   +1 more source