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The Human Placenta [PDF]

open access: bronzeJournal of Clinical Pathology, 1970
This magnificent treatise on the human placenta is a definitive work on the normal structure of that vital and often-neglected organ. The usual book, like a bottle of wine, is soon finished, leaving only more or less pleasant memories. This book, however, large in size and broad in scope, is more like a whole wine cellar—to be read and enjoyed over a ...
W. J. Hamilton
  +9 more sources

Serotonin system in the human placenta – the knowns and unknowns [PDF]

open access: yesFrontiers in Endocrinology, 2022
The biogenic monoamine serotonin (5-hydroxytryptamine, 5-HT) is a chemical messenger widely distributed in the brain and various other organs. Its homeostasis is maintained by the coordinated activity of a variety of proteins, including enzymes of ...
Maja Perić   +4 more
doaj   +2 more sources

Advanced magnetic resonance imaging in human placenta: insights into fetal growth restriction and congenital heart disease [PDF]

open access: yesFrontiers in Cardiovascular Medicine
Placental function plays a crucial role in fetal development, as it serves as the primary interface for delivery of nutrients and oxygen from the mother to fetus.
Eric Sadiku   +13 more
doaj   +2 more sources

Breaking rules: the complex relationship between DNA methylation and X-chromosome inactivation in the human placenta [PDF]

open access: yesBiology of Sex Differences
Background The human placenta is distinct from most organs due to its uniquely low-methylated genome. DNA methylation (DNAme) is particularly depleted in the placenta at partially methylated domains and on the inactive X chromosome (Xi) in XX samples ...
Amy M Inkster   +6 more
doaj   +2 more sources

C1431T Variant of PPARγ Is Associated with Preeclampsia in Pregnant Women

open access: yesLife, 2021
Peroxisome proliferator-activated receptor γ (PPARγ) is essential for placental development, whose SNPs have shown increased susceptibility to pregnancy-related diseases, such as preeclampsia.
Fulin Liu   +7 more
doaj   +1 more source

Tropism and Infectivity of Pandemic Influenza A H1N1/09 Virus in the Human Placenta

open access: yesViruses, 2022
Influenza virus infection in pregnant women may put the fetus at higher risk; however, to date, there has been no detailed research about the expression of influenza virus receptors in the human placenta.
Yan-Na Xiao   +3 more
doaj   +1 more source

Integrating High-Throughput Approaches and in vitro Human Trophoblast Models to Decipher Mechanisms Underlying Early Human Placenta Development

open access: yesFrontiers in Cell and Developmental Biology, 2021
The placenta is a temporary but pivotal organ for human pregnancy. It consists of multiple specialized trophoblast cell types originating from the trophectoderm of the blastocyst stage of the embryo.
Bum-Kyu Lee, Jonghwan Kim
doaj   +1 more source

Isolation and characterization of galectin-1 binding proteins from human placenta [PDF]

open access: yesJournal of the Serbian Chemical Society, 2000
Galectin-1 binding proteins were isolated from human placenta by affinity chromatography on a column with immobilized endogenous lectin. The molecular masses of the isolated proteins of 170, 67 and 56 kDa were estimated by gel filtration and SDS-
Janković Miroslava
doaj   +3 more sources

Development of the human placenta [PDF]

open access: yesDevelopment, 2019
ABSTRACT The placenta is essential for normal in utero development in mammals. In humans, defective placental formation underpins common pregnancy disorders such as pre-eclampsia and fetal growth restriction. The great variation in placental types across mammals means that animal models have been of limited use in understanding human ...
Turco, Margherita Y, Moffett, Ashley
openaire   +4 more sources

Genomic imprinting in human placentation

open access: yesReproductive Medicine and Biology, 2022
Background Genomic imprinting (GI) is a mammalian‐specific epigenetic phenomenon that has been implicated in the evolution of the placenta in mammals.
Eri H. Kobayashi   +6 more
doaj   +1 more source

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