Results 151 to 160 of about 223,303 (264)

A transcriptomic comparison of in vitro models of the human placenta. [PDF]

Placenta
Lapehn S, Nair S, Firsick EJ, MacDonald J, Thoreson C, Litch JA, Bush NR, Kadam L, Girard S, Myatt L, Prasad B, Sathyanarayana S, Paquette AG.   +12 more
europepmc   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Bisphenol Analog‐Induced Cytotoxicity: Unraveling Endoplasmic Reticulum (ER) Stress and Apoptotic Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is increasingly replaced by structural analogs, yet their safety remains insufficiently characterized. This study investigated whether BPA and selected analogs, bisphenol AF (BPAF), bisphenol AP (BPAP), bisphenol P (BPP), and bisphenol E (BPE), induce cytotoxicity through activation of endoplasmic reticulum (ER) stress and ...
Rafia Afroze Rifa, Ramon Lavado
wiley   +1 more source

Human Placenta Hydrolysate Protects Against Acetaminophen-Induced Liver Injury in Mice. [PDF]

Biomedicines
Hwang I, Kang CG, Lim SJ, Kim HJ, Kang R, Jeon SH, Lee SH, Kim JW, Kang JS.   +8 more
europepmc   +1 more source

Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice, M. Bertazzo, A. F. Tabaran, M. Parolini, R. P. Popa, A. Pintea, L. J. Spicer, A‐L. Nagy, F. Caloni   +8 more
wiley   +1 more source

Human placenta-derived endothelial progenitor cells: an animal-free culture system for efficient expansion. [PDF]

Biol Res
Yuan S, Li M, Wang J, Ju W, Huang Y, Li Y, Fan H, Zeng L.   +7 more
europepmc   +1 more source

Assessing Metabolic and Reproductive Consequences of Prenatal Paracetamol Exposure in Female CD1 Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari, Deniz Bozdag, Elif İnce‐Erguc, Aylin Buhur, Cansin Sirin Tomruk, Suna Sabuncuoglu, Altug Yavasoglu, Hande Gurer‐Orhan   +7 more
wiley   +1 more source

Profiling the cell-specific small non-coding RNA transcriptome of the human placenta. [PDF]

Sci Rep
Telkar N, Hui D, Peñaherrera MS, Yuan V, Martinez VD, Stewart GL, Beristain AG, Lam WL, Robinson WP.   +8 more
europepmc   +1 more source

sFlt‐1/PlGF Ratio in the Diagnosis of Preeclampsia on the MAGLUMI X3 Analyzer

Journal of Clinical Laboratory Analysis, EarlyView.
We compared the analytical and clinical performance of MAGLUMI X3 (Snibe) and Elecsys (Roche) for measuring sFlt‐1, PlGF, and their ratio in women hospitalized at the Department of Gynecology and Obstetrics, University Hospital in Pilsen. In a single‐center, real‐world cohort (192 samples from 164 patients), method comparison showed good agreement ...
Pavel Broz, Simona Kukralova, Zdenek Sebesta, Katerina Brslicova, Michal Kozerovsky, Jaroslav Racek, Daniel Rajdl   +6 more
wiley   +1 more source

The multifaceted roles of the transcriptional coactivator TAZ in extravillous trophoblast development of the human placenta. [PDF]

Proc Natl Acad Sci U S A
Meinhardt G, Waldhäusl H, Lackner AI, Wächter J, Maxian T, Höbler AL, Vondra S, Kunihs V, Saleh L, Haslinger P, Kiraly P, Szilagyi A, Than NG, Pollheimer J, Haider S, Knöfler M.   +15 more
europepmc   +1 more source