Results 31 to 40 of about 8,929,794 (358)

Genomic imprinting in human placentation

Reproductive Medicine and Biology, 2022
Background Genomic imprinting (GI) is a mammalian‐specific epigenetic phenomenon that has been implicated in the evolution of the placenta in mammals.
Eri H. Kobayashi, Shun Shibata, Akira Oike, Norio Kobayashi, Hirotaka Hamada, Hiroaki Okae, Takahiro Arima   +6 more
doaj   +1 more source

Serotonin system in the human placenta – the knowns and unknowns

Frontiers in Endocrinology, 2022
The biogenic monoamine serotonin (5-hydroxytryptamine, 5-HT) is a chemical messenger widely distributed in the brain and various other organs. Its homeostasis is maintained by the coordinated activity of a variety of proteins, including enzymes of ...
Maja Perić, Ivona Bečeheli, Lipa Čičin-Šain, Gernot Desoye, Jasminka Štefulj   +4 more
doaj   +1 more source

Placental syncytiotrophoblast constitutes a major barrier to vertical transmission of Listeria monocytogenes. [PDF]

, 2010
Listeria monocytogenes is an important cause of maternal-fetal infections and serves as a model organism to study these important but poorly understood events. L.
A Beham, A Le Monnier, A Moffett, A Shen, AI Bakardjiev, AI Bakardjiev, AI Bakardjiev, AJ Teberg, AM Carter, Anna I. Bakardjiev, AV Lallemand, B Swaminathan, BF King, C Coutifaris, C Floridon, C Kocks, C Sundstrom, CA Kirkbride, CD Ockleford, DA Drevets, DA Drevets, DA Portnoy, DA Portnoy, David S. Schneider, DK Bishop, E Maidji, E Mylonakis, EG Pamer, G Scheuner, H Bierne, H Koi, HM Cobe, IJ Glomski, J Mengaud, J Skoble, J Trowsdale, JA Theriot, Jennifer R. Robbins, JR Robbins, K Benirschke, K Red-Horse, K Red-Horse, Kasia M. Skrzypczynska, KS Kim, L Forner, L Vicovac, LG Tilney, LM Brown, M Berryman, M Lecuit, M Lecuit, M Lecuit, M O'Riordan, M Pentecost, Mirhan Kapidzic, NM Hunkapiller, O Disson, O Genbacev, O Genbacev, O Genbacev, P Cossart, PB Medawar, PD Barnes, PM Drake, RK Miller, RL Goldenberg, S Fisher, S Jones, S Kaur, S Notermans, SJ Cantle, SJ Fisher, SJ Fisher, SR Sooranna, T Kajii, T Rajabian, T Wollert, TH Schiebler, Varvara B. Zeldovich, Y Huang, Y Shen, Y Zhou, Z Vacek   +82 more
core   +3 more sources

Human placenta has no microbiome but can harbour potential pathogens

Nature, 2019
We sought to determine whether pre-eclampsia, spontaneous preterm birth or the delivery of infants who are small for gestational age were associated with the presence of bacterial DNA in the human placenta. Here we show that there was no evidence for the
M. D. de Goffau, S. Lager, U. Sovio, F. Gaccioli, E. Cook, Sharon J. Peacock, J. Parkhill, D. S. Charnock-Jones, Gordon C. S. Smith   +8 more
semanticscholar   +1 more source

Human placenta and trophoblast development: key molecular mechanisms and model systems

Cellular and Molecular Life Sciences, 2019
Abnormal placentation is considered as an underlying cause of various pregnancy complications such as miscarriage, preeclampsia and intrauterine growth restriction, the latter increasing the risk for the development of severe disorders in later life such
M. Knöfler, S. Haider, L. Saleh, J. Pollheimer, T. Gamage, J. James   +5 more
semanticscholar   +1 more source

Immunosuppressive Protein Signatures Carried by Syncytiotrophoblast-Derived Exosomes and Their Role in Human Pregnancy

Frontiers in Immunology, 2021
The syncytiotrophoblast (STB) of human placenta constitutively and throughout pregnancy produces and secretes exosomes - nanometer-sized membrane-bound extracellular vesicles from the endosomal compartment that convey cell-cell contact ‘by proxy ...
Lucia Mincheva-Nilsson
doaj   +1 more source

Transport of persistent organic pollutants across the human placenta [PDF]

, 2014
Environment International 65, 107-115 ...
Fernández-Somoano, A, Fernández-Somoano, A, Fernández-Somoano, A, Grimalt, JO, Grimalt, JO, Grimalt, JO, Tardon, A, Tardon, A, Tardon, A, Vizcaino, E   +9 more
core   +1 more source

Ambient black carbon particles reach the fetal side of human placenta

Nature Communications, 2019
Particle transfer across the placenta has been suggested but to date, no direct evidence in real-life, human context exists. Here we report the presence of black carbon (BC) particles as part of combustion-derived particulate matter in human placentae ...
H. Bové, E. Bongaerts, E. Slenders, E. Bijnens, N. Saenen, W. Gyselaers, P. Van Eyken, M. Plusquin, M. Roeffaers, M. Ameloot, T. Nawrot   +10 more
semanticscholar   +1 more source

The haemodynamics of the human placenta in utero

bioRxiv, 2020
We have used MRI to provide important new insights into the function of the human placenta in utero. We have measured slow net flow and high net oxygenation in the placenta in vivo, which are consistent with efficient delivery of oxygen from mother to ...
N. Dellschaft, G. Hutchinson, Simon M. Shah, N. Jones, C. Bradley, L. Leach, Craig Platt, R. Bowtell, P. Gowland   +8 more
semanticscholar   +1 more source

The Effect of Genetic Variation on the Placental Transcriptome in Humans

Frontiers in Genetics, 2019
The knowledge of genetic variants shaping human placental transcriptome is limited and they are not cataloged in the Genotype-Tissue Expression project.
Triin Kikas, Kristiina Rull, Kristiina Rull, Kristiina Rull, Robin N. Beaumont, Rachel M. Freathy, Maris Laan   +6 more
doaj   +1 more source