Results 41 to 50 of about 8,929,794 (358)

Unique features and emerging in vitro models of human placental development

Reproductive Medicine and Biology, 2020
Background The placenta is an essential organ for the normal development of mammalian fetuses. Most of our knowledge on the molecular mechanisms of placental development has come from the analyses of mice, especially histopathological examination of ...
Shun Shibata, Eri H. Kobayashi, Norio Kobayashi, Akira Oike, Hiroaki Okae, Takahiro Arima   +5 more
doaj   +1 more source

Preliminary Study of Iron Concentration in the Human Placenta in Twin Pregnancies

Biomolecules, 2023
Background: Pregnancy significantly increases the demand for iron (Fe) in the female body to facilitate maternal blood volume expansion, placental development, and fetal growth. As Fe flux in pregnancy is significantly influenced by the placenta, the aim
Konrad Grzeszczak, Patrycja Kapczuk, Patrycja Kupnicka, Maciej Mularczyk, Sebastian Kwiatkowski, Dariusz Chlubek, Danuta Kosik-Bogacka   +6 more
doaj   +1 more source

The Human Pregnancy-Specific Glycoprotein Genes are Tightly Linked on the Long Arm of Chromosome 19 and are Coordinately Expressed [PDF]

, 1990
The pregnancy-specific glycoprotein (PSG) genes encode a group of proteins which are found in large amounts in placenta and maternal serum. In situ hybridization analyses of metaphase chromosomes reveal that all the human pregnancy-specific glycoprotein (
Barnett, Barnett, Barnett, Benton, Bohn, Chan, Chomczynski, Feinberg, Fiddes, Grunert, Hefta, Hinoda, Jean, Kamarck, Khan, Khan, Kolbinger, Lathe, Lin, Maniatis, Neumaier, Niemann, Oikawa, Oikawa, Oikawa, Paxton, Perry, Rooney, Rudert, Sanger, Streydio, Takami, Tatarinov, Thompson, Thompson, Thompson, Watanabe, Watanabe, Willcocks, Zimmermann, Zimmermann   +40 more
core   +1 more source

Oxidative stress stimulates alpha-tocopherol transfer protein in human trophoblast tumor cells BeWo [PDF]

, 2012
alpha-Tocopherol transfer protein (alpha-TTP) has been identified as the major intracellular transport protein for the antioxidant vitamin E (alpha-Tocopherol).
Etzl, Ronny P., Jeschke, Udo, Kuhn, Christina, Makrigiannakis, Antonis, Poeschl, Johannes M., Rotzoll, Daisy E., Schulze, Sandra, Vrekoussis, Thomas   +7 more
core   +1 more source

Development of the human placenta

Development, 2019
The placenta is essential for normal in utero development in mammals. In humans, defective placental formation underpins common pregnancy disorders such as pre-eclampsia and fetal growth restriction.
M. Turco, A. Moffett
semanticscholar   +1 more source

Localized Expression of Histamine H1 Receptors in Syncytiotrophoblast Cells of Human Placenta

Journal of Pharmacological Sciences, 2006
The previous Northern blot analysis and in situ hybridization studies showed that histamine H1-receptor (H1R) mRNA is expressed in human placenta and suggested that H1R plays some roles in the function of placenta in pregnancy. To investigate further, it
Kazuto Matsuyama, Tatsuya Ichikawa, Yuichi Nitta, Yoshio Ikoma, Kazutaka Ishimura, Shuhei Horio, Hiroyuki Fukui   +6 more
doaj   +1 more source

Acellular Human Placenta Small-Diameter Vessels as a Favorable Source of Super-Microsurgical Vascular Replacements: A Proof of Concept

Bioengineering, 2023
In this study, we aimed to evaluate the human placenta as a source of blood vessels that can be harvested for vascular graft fabrication in the submillimeter range. Our approach included graft modification to prevent thrombotic events.
Florian Falkner, Simon Andreas Mayer, Benjamin Thomas, Sarah Onon Zimmermann, Sonja Walter, Patrick Heimel, Wilko Thiele, Jonathan Paul Sleeman, Amir Khosrow Bigdeli, Herbert Kiss, Bruno Karl Podesser, Ulrich Kneser, Helga Bergmeister, Karl Heinrich Schneider   +13 more
doaj   +1 more source

The importance of imprinting in the human placenta. [PDF]

, 2010
As a field of study, genomic imprinting has grown rapidly in the last 20 years, with a growing figure of around 100 imprinted genes known in the mouse and approximately 50 in the human. The imprinted expression of genes may be transient and highly tissue-
A Lewis, A Plagge, A Thurston, AC Enders, AC Ferguson-Smith, AC Ferguson-Smith, AI Diplas, AL Fowden, AM Carter, AM Carter, Anne C. Ferguson-Smith, BM Cattanach, BV Skryabin, C Gicquel, CB Oudejans, CP Sibley, D Frank, D Haig, D Haig, D Haig, D Mancini-DiNardo, D Monk, D Monk, D Monk, D Monk, D Takai, D Umlauf, DP Barlow, DR Arnold, E Li, F Ding, F Guillemot, F Guillemot, F Ubeda, FM Smith, G Pardi, Gudrun E. Moore, GV Fitzpatrick, H Cui, H Munier-Lehmann, I Hatada, I Iglesias-Platas, IM Buntinx, IY Yotova, J Liu, J McGrath, J McMinn, JA Graves, Jennifer M. Frost, JL Thorvaldsen, JM Bowen, JR Engel, JY Shin, K Green, K Hannula, K Knox, K Mitsuya, K Takahashi, KD Tremblay, KG Pringle, L Lefebvre, L Lunghi, L Redrup, M Charalambous, M Charalambous, M Constancia, M Constancia, M Kaneda, MA Frevel, MA Surani, MD Dean, MM Lau, MP Hitchins, MP Lee, MS Bartolomei, N Blagitko, N Kanayama, NM Gude, P Arnaud, P Georgiades, PA Leighton, PM Coan, PM Coan, Q Wang, R Terranova, RD Nicholls, RJ Baker, S Abu-Amero, S Apostolidou, SJ Tunster, SM Davies, ST da Rocha, T Ludwig, T Miyamoto, T Moore, T Sahoo, TJ Cole, TM DeChiara, TM DeChiara, U von Rango, V Romanelli, W Mayer, W Reik, WN Cooper, Y Yan, YS Moon, ZQ Wang   +106 more
core   +3 more sources

Combined diffusion‐relaxometry MRI to identify dysfunction in the human placenta [PDF]

Magnetic Resonance in Medicine, 2018
A combined diffusion‐relaxometry MR acquisition and analysis pipeline for in vivo human placenta, which allows for exploration of coupling between T2* and apparent diffusion coefficient (ADC) measurements in a sub 10‐minute scan time.
P. Slator, J. Hutter, M. Palombo, Laurence H. Jackson, Alison Ho, Eleftheria Panagiotaki, L. Chappell, M. Rutherford, J. Hajnal, D. Alexander   +9 more
semanticscholar   +1 more source

Modeling human trophoblast, the placental epithelium at the maternal fetal interface. [PDF]

, 2020
Appropriate human trophoblast lineage specification and differentiation is crucial for the establishment of normal placentation and maintenance of pregnancy. However, due to the lack of proper modeling systems, the molecular mechanisms of these processes
Bui, Tony, Horii, Mariko, Parast, Mana M, Touma, Ojeni   +3 more
core   +1 more source