Inhibition of human FcγRIII prevents platelet destruction in a dual-humanized murine model of FNAIT. [PDF]
Tawhidi Z +11 more
europepmc +1 more source
Reprogramming rather than depleting immunity: Targeting the CD38-NAD<sup>+</sup> axis in antibody-mediated autoimmunity. [PDF]
Li H, Wei J, Zhang L.
europepmc +1 more source
Anti-Human Platelet Antigen-1a Immunoglobulin G Preparation Intended to Prevent Fetal and Neonatal Alloimmune Thrombocytopenia. [PDF]
Weng YJ +5 more
europepmc +1 more source
Fetal and Neonatal Alloimmune Thrombocytopenia in the Middle East: A Confirmed Case Highlighting Immunogenetic Diversity and Evidence-Based Neonatal Management. [PDF]
Haj Mohamad H +6 more
europepmc +1 more source
ABSTRACT Despite substantial clinical benefit from immune checkpoint inhibitors (ICI), advanced melanoma remains challenging due to frequent treatment resistance. Resistance may be intrinsic (primary) or emerge over time (secondary). Biomarkers predicting distinct resistance phenotypes before therapy are lacking.
Julian Kött +17 more
wiley +1 more source
Dual hemostatic defects in Glanzmann thrombasthenia and von Willebrand disease: functional characterization of ITGA2B and dominant-negative von Willebrand factor variants. [PDF]
Zhang Y +14 more
europepmc +1 more source
Severe surgically confirmed endometriosis was associated with a lower prevalence of steatotic liver disease than non‐severe disease. Higher estradiol levels may partly explain this inverse hepatic–reproductive association, supporting integrated gynecologic and hepatologic risk assessment.
Jung Hyun Park +5 more
wiley +1 more source
Design of a modified platelet immunofluorescence test to assess platelet-reactive antibody burden and its association with platelet functional exhaustion and clinical features in chronic immune thrombocytopenia. [PDF]
Hosseini E +5 more
europepmc +1 more source
Advances in Immunological Combination Therapy for Colorectal Cancer
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu +7 more
wiley +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source

