Results 231 to 240 of about 8,090,431 (285)

Anti-HPA-1a IgG3 subclass antibodies induce strong platelet phagocytosis. [PDF]

open access: yesBr J Haematol
Schmidt S   +5 more
europepmc   +1 more source

Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf   +8 more
wiley   +1 more source

Piper nigrum Has an Antitumor Effect Through Regulation of the Phosphatidylinositol 3‐Kinase Signaling Pathway in a Murine Model of Acute Myeloid Leukemia

open access: yesPhytotherapy Research, EarlyView.
Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo   +3 more
wiley   +1 more source

Integrated Immunological Engineering Platform for Scalable Production of iPSC-Derived Megakaryocytes. [PDF]

open access: yesHLA
Dettmer R   +6 more
europepmc   +1 more source

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