Results 51 to 60 of about 9,322,993 (252)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Efficient Human Pose Estimation in Hierarchical Context

IEEE Access, 2019
Most existing human pose estimation methods focus on enhancing the accuracy performance alone while ignoring the critical model efficiency issue. This dramatically limits their scalability and deployability in large-scale applications.
Feng Zhang, Xiatian Zhu, Mao Ye
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Efficient Monocular Human Pose Estimation Based on Deep Learning Methods: A Survey

IEEE Access
Human pose estimation (HPE) is a crucial computer vision task with a wide range of applications in sports medicine, healthcare, virtual reality, and human-computer interaction.
Xuke Yan, Bo Liu, Guangzhi Qu
doaj   +1 more source

Hierarchical Adversarial Network for Human Pose Estimation

IEEE Access, 2019
This paper presents a novel adversarial deep neural network to estimate human poses from still images, such as those obtained from CCTV and the Internet-of-Things (IoT) devices.
Ibrahim Radwan, Nour Moustafa, Byron Keating, Kim-Kwang Raymond Choo, Roland Goecke   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Head pose estimation for a domestic robot

, 2011
Gaze direction is an important communicative cue. In order to use this cue for human-robot interaction, software needs to be developed that enables the estimation of head pose.
Billard, A., Cuijpers, R.H., Kahn, P., Adams, J.A,, Pol, van der, D., Juola, J.F., Trafton, G.   +6 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

PRAMGCN-Net: 3D Human Pose Estimation With a Parameterized Routing Adjacency Modulation Graph Convolutional Network

IEEE Access
Human pose estimation reconstructs 3D human joint positions from monocular images or videos, enabling applications in healthcare, sports, AR/VR, and animation. The challenge lies in depth ambiguity, temporal coherence, and complex motion patterns. Recent
Andy Pramono, I-Cheng Chang, Betty Dewi Puspasari   +2 more
doaj   +1 more source