Results 91 to 100 of about 2,739,043 (309)

ORGANIZATIONAL TRAINING IN MANUFACTURING FIRMS AND ADVANCED MANUFACTURING TECHNOLOGIES [PDF]

open access: yes
The introduction of new microelectronic technologies in the manufacturing process forces companies to adapt human resource strategy to the changes in the workplace.
Ana Canto, Ana Cantorna, Isabel Diéguez
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CONTINUOUS PROFESSIONAL TRAINING WITHIN THE LEARNING ORGANIZATION [PDF]

open access: yes
Continuous professional training represents a systematic approach of learning and development, having as purpose the improvement of the individual’s, team’s or organization’s efficacy. This can play a very important part and can affect not only the human
Sorina-Mihaela MARDAR
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Knowledge Collaboration: Working with Data and Web Specialists [PDF]

open access: yes, 2015
When resources are finite, people strive to manage resources jointly (if they do not rudely take possession of them). Organizing helps achieve—and even amplify—common purpose but often succumbs in time to organizational silos, teaming for the sake of ...
Serrat, Olivier
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Optimizing human resources competence in the era of digital transformation as a strategic framework for crime prevention and handling

open access: yesJurnal Inovasi Ilmu Sosial dan Politik
The fluctuating crime rate in Gorontalo City necessitates adaptive and responsive police institutions. Strengthening human resources (HR) at the Gorontalo City Resort Police (Polresta) is essential, as personnel play a key role in maintaining public ...
Saadia Alamri   +2 more
doaj   +1 more source

Performance Management and Work Performance Appraisal [PDF]

open access: yesSocietas et Iurisprudentia, 2014
Human resources management has gone through many changes in the past twenty to thirty years and therefore, it is necessary to consider it from the historical point of view.
Iveta Posoldová
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

How Will Competition Change Human Resource Management in Retail Banking? A Strategic Perspective [PDF]

open access: yes
The proposition that the way firms manage their labor forces should be consistent with their organization strategy might seem both obvious and noncontroversial.
Larry W. Hunter
core  

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