Results 51 to 60 of about 133,164 (249)
Quercetin pentaacetate inhibits in Vitro Human Respiratory Syncytial Virus adhesion.
Virus Research, 2019 Human respiratory syncytial virus (hRSV) is one of the main etiological agents of diseases of the lower respiratory tract and is often responsible for the hospitalization of children and the elderly.
B. Lopes +14 more
semanticscholar +1 more source
Contribution of IDO to human respiratory syncytial virus infection [PDF]
Journal of Leukocyte Biology, 2019 Abstract IDO is an enzyme that participates in the degradation of tryptophan (Trp), which is an essential amino acid necessary for vital cellular processes. The degradation of Trp and the metabolites generated by the enzymatic activity of IDO can have immunomodulating effects, notably over T cells, which are particularly sensitive to the
Benavente, Felipe M. +6 more
openaire +3 more sources
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Influenza and Other Respiratory Viruses, 2021 The hospitalized acute respiratory tract infection (HARTI) study used the Respiratory Intensity and Impact Questionnaire (RiiQ™) Symptom Scale, derived from FluiiQ™, to assess and compare the burden of respiratory infection symptoms for patients with ...
A. Falsey +9 more
semanticscholar +1 more source
Respiratory viruses in mechanically ventilated patients: a pilot study
BMC Pulmonary Medicine, 2020 Background Respiratory virome is an integral part of the human microbiome and its characterization may contribute to a better understanding of the changes that arise in the disease and, consequently, influence the approach and treatment of patients with ...
Raquel Nazareth +10 more
doaj +1 more source
Molecular Mimicry between Respiratory Syncytial Virus F Antigen and the Human Proteome
Global Medical Genetics, 2023 This study examined respiratory syncytial virus (RSV) F glycoprotein (gp) antigen for molecular mimicry with the human proteome. It was found that the viral antigen presents an impressive number of pentapeptides (namely, 525 out of 570) in common with ...
Darja Kanduc
doaj +1 more source
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses
Nature Microbiology, 2017 Human respiratory syncytial virus (hRSV) is a major cause of morbidity and mortality in the paediatric, elderly and immune-compromised populations1,2. A gap in our understanding of hRSV disease pathology is the interplay between virally encoded immune ...
S. Chatterjee +16 more
semanticscholar +1 more source
A novel host factor for human respiratory syncytial virus [PDF]
Communicative & Integrative Biology, 2017 Human respiratory syncytial virus (RSV) is the leading viral cause of severe lower respiratory disease in young children worldwide. As part of a genome-wide siRNA screen, we recently discovered that actin-related protein 2 (ARP2) is a host factor in the RSV replication cycle.
Masfique Mehedi +2 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal +21 more
wiley +1 more source
Canadian Journal of Infectious Diseases and Medical Microbiology, 2021 Background. Acute respiratory tract infections (ARTIs) are the leading cause of illnesses in children. Human respiratory syncytial virus (HRSV) and human parainfluenza viruses (HPIVs) are among the most common etiologic agents associated with viral ...
Zahra Ramezannia +6 more
doaj +1 more source