Results 71 to 80 of about 133,164 (249)

Prevalence of human respiratory syncytial virus circulating in Iran.

Journal of Infection and Public Health, 2016
Respiratory syncytial virus (RSV) is a leading cause of acute respiratory infection during early childhood and is associated with a great burden on patients, parents, and society. While no treatment is yet available, results from recent phase 2 clinical trials of cell-entry inhibitors and RSV vaccines are promising. To prepare for introduction of these
V. Salimi, Masoumeh Tavakoli-Yaraki, J. Yavarian, Louis J Bont, T. Mokhtari-azad   +4 more
semanticscholar   +5 more sources

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis

The Lancet Global Health, 2019
Summary: Background: Influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus are the most common viruses associated with acute lower respiratory infections in young children (
You Li, MSc, Rachel M Reeves, PhD, Xin Wang, MSc, Quique Bassat, ProfMD, W Abdullah Brooks, MD, Cheryl Cohen, PhD, David P Moore, PhD, Marta Nunes, PhD, Barbara Rath, ProfPhD, Harry Campbell, ProfMD, Harish Nair, ProfPhD, Sozinho Acacio, Wladimir J Alonso, Martin Antonio, Guadalupe Ayora Talavera, Darmaa Badarch, Vicky L Baillie, Gisela Barrera-Badillo, Godfrey Bigogo, Shobha Broor, Dana Bruden, Philippe Buchy, Peter Byass, James Chipeta, Wilfrido Clara, Duc-Anh Dang, Carla Cecília de Freitas Lázaro Emediato, Menno de Jong, José Alberto Díaz-Quiñonez, Lien Anh Ha Do, Rodrigo A Fasce, Luzhao Feng, Mark J Ferson, Angela Gentile, Bradford D Gessner, Doli Goswami, Sophie Goyet, Carlos G Grijalva, Natasha Halasa, Orienka Hellferscee, Danielle Hessong, Nusrat Homaira, Jorge Jara, Kathleen Kahn, Najwa Khuri-Bulos, Karen L Kotloff, Claudio F Lanata, Olga Lopez, Maria Renee Lopez Bolaños, Marilla G Lucero, Florencia Lucion, Socorro P Lupisan, Shabir A Madhi, Omphile Mekgoe, Cinta Moraleda, Jocelyn Moyes, Kim Mulholland, Patrick K Munywoki, Fathima Naby, Thanh Hung Nguyen, Mark P Nicol, D James Nokes, Daniel E Noyola, Daisuke Onozuka, Nandhini Palani, Yong Poovorawan, Mustafizur Rahman, Kaat Ramaekers, Candice Romero, Elizabeth P Schlaudecker, Brunhilde Schweiger, Phil Seidenberg, Eric A F Simoes, Rosalyn Singleton, Sujatha Sistla, Katharine Sturm-Ramirez, Nungruthai Suntronwong, Agustinus Sutanto, Milagritos D Tapia, Somsak Thamthitiwat, Ilada Thongpan, Gayani Tillekeratne, Yeny O Tinoco, Florette K Treurnicht, Claudia Turner, Paul Turner, Rogier van Doorn, Marc Van Ranst, Benoit Visseaux, Sunthareeya Waicharoen, Jianwei Wang, Lay-Myint Yoshida, Heather J Zar   +92 more
doaj   +1 more source

Assessment of Illness Severity in Adults Hospitalized With Acute Respiratory Tract Infection due to Influenza, Respiratory Syncytial Virus, or Human Metapneumovirus

Influenza and Other Respiratory Viruses
Influenza, respiratory syncytial virus (RSV), and human metapneumovirus (hMPV) are common respiratory viruses causing similar symptoms. Optimal tools to assess illness severity for these viruses have not been defined.
A. Falsey, E. Walsh, Stacey L. House, Yannick Vandendijck, M. Stevens, Eric Chan, G. Ispas   +6 more
semanticscholar   +1 more source

Human Respiratory Syncytial Virus and Streptococcus pneumoniae Infection in Wild Bonobos

EcoHealth, 2018
Despite being important conservation tools, tourism and research may cause transmission of pathogens to wild great apes. Investigating respiratory disease outbreaks in wild bonobos, we identified human respiratory syncytial virus and Streptococcus ...
Kim Grützmacher, Verena Keil, Sonja Metzger, Livia Wittiger, Ilka Herbinger, S. Calvignac-Spencer, K. Mätz-Rensing, Olivia Haggis, L. Savary, Sophie Köndgen, F. Leendertz   +10 more
semanticscholar   +1 more source

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Functional Impairment of Mononuclear Phagocyte System by the Human Respiratory Syncytial Virus

Frontiers in Immunology, 2017
The mononuclear phagocyte system (MPS) comprises of monocytes, macrophages (MΦ), and dendritic cells (DCs). MPS is part of the first line of immune defense against a wide range of pathogens, including viruses, such as the human respiratory syncytial ...
Karen Bohmwald, Janyra A. Espinoza, Raúl A. Pulgar, Evelyn L. Jara, A. Kalergis   +4 more
semanticscholar   +1 more source

The Story behind the Science: On the discovery of respiratory syncytial virus

mBio
Respiratory syncytial virus (RSV) was discovered in 1956 by the laboratory of Robert Chanock after its isolation from children with upper respiratory infections.
Arturo Casadevall, Philip R. Roane, Thomas Shenk, Bernard Roizman   +3 more
doaj   +1 more source

Human Metapneumovirus and Severity of Respiratory Syncytial Virus Disease

Emerging Infectious Diseases, 2004
We screened 23 children with severe respiratory syncytial virus (RSV) disease and 23 children with mild RSV disease for human metapneumovirus (HMPV). Although HMPV was circulating in Connecticut, none of the 46 RSV-infected patients tested positive for ...
Isaac Lazar, Carla Weibel, James Dziura, David Ferguson, Marie L. Landry, Jeffrey S. Kahn   +5 more
doaj   +1 more source