Results 111 to 120 of about 3,886,019 (315)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
بناء مقیاس لتقییم درجة ممارسة الحقوق الإنسانیة الوظیفیة بالمؤسسات التعلیمیة: دراسة تطبیقیة على موظفی وموظفات جامعة أم القرى بمکة المکرمة Creating a scale to assess the degree of Functional human rights practice in educational institutions: An applied study on the employees of Umm Al-Qura University in Makkah [PDF]
, 2020 حیاة بنت محمد بن سعد الحربی
openalex +1 more source
Human Rights Accountability Through Treaty Bodies: Examining Human Rights Treaty Monitoring for Water and Sanitation [PDF]
, 2015 Framing scholarship on human rights accountability through treaty bodies, this article examines the water and sanitation content of state human rights reporting to the United Nations Committee on Economic, Social and Cultural Rights.
Kim, Yuna, Meier, Benjamin Mason
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2015 To assess the epidemiological risk of introduction of serious infectious diseases in the pre-Olympic period defined list of dangerous and exotic infections and held assessment ofpotential danger threatening.
B. P Kuzkin +14 more
doaj
Human Rights in Global Health Governance [PDF]
, 2018 Human rights frame global health governance. In codifying a normative foundation for global governance in the aftermath of World War II, states came together under the auspices of an emergent United Nations (UN) to develop human rights under ...
Gostin, Lawrence O. +2 more
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
International human rights lawyers tend to focus on establishing the universality of human rights rather than on improving the usefulness of human rights in addressing local problems.
De Feyter, Koen
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Do Choice & Speed of Reforms Matter for Human Rights During Transition? [PDF]
, 2008 Conventional wisdom posits absence of systematic relationship between economic reforms and human rights. Taking the case of transition economies, Vadlamannati & Soysa (2008) shows significant positive relationship between economic reforms and various ...
Vadlamannati, Krishna Chaitanya
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