Results 101 to 110 of about 1,366,283 (308)

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Systems and human science, for safety, security, and dependability : seleced papers of the 1st International Symposium SSR2003, Osaka, Japan, November 2003 /

open access: yes, 2005
Our society keeps growing with a large number of complicated machines and systems, while we are spending our diverse lives. The number of aged people has been increasing in the society.
Arai, Tatsuo.   +6 more
core  

Air traffic management safety challenges [PDF]

open access: yes, 2007
The primary goal of the Air Traffic Management (ATM) system is to control accident risk. ATM safety has improved over the decades for many reasons, from better equipment to additional safety defences.
Brooker, Peter
core  

Design-Based Safety: Reliability

open access: yes, 2015
As both business enterprise and governmental activities become automated, reliability will be the measure of performance. The term “reliability” establishes an actual value of absolute dependable failure-free performance from all hazardous conditions or ...
MacCollum, David
core   +1 more source

Numerical study of the influence of the rupture of burst discs on shock wave propagation in hydrogen-oxygen detonation tube

open access: yesCase Studies in Thermal Engineering
Hydrogen-oxygen detonation tube has a wide range of applications. However, the role of burst discs is often oversimplified, overlooking the detrimental effects of their non-ideal rupture on shock wave propagation.
Yuhan Song   +6 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Patient safety in health care professional educational curricula: examining the learning experience

open access: yes, 2009
This study has investigated the formal and informal ways pre-registration students from four healthcare professions learn about patient safety in order to become safe practitioners.
Steven, Alison   +2 more
core  

Management of Fibrosis: The Mesenchymal Stromal Cells Breakthrough

open access: yesStem Cells International, 2014
Fibrosis is the endpoint of many chronic inflammatory diseases and is defined by an abnormal accumulation of extracellular matrix components. Despite its slow progression, it leads to organ malfunction. Fibrosis can affect almost any tissue.
Benoît Usunier   +3 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

On-road driving studies to understand why drivers behave as they do at regional rail level crossings

open access: yes, 2013
Improving safety at rail level crossings is an important part of both road and rail safety strategies. While low in number, crashes between vehicles and trains at level crossings are catastrophic events typically involving multiple fatalities and serious
Salmon, P.B.   +12 more
core  

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