Results 171 to 180 of about 1,366,283 (308)

First-In-Human Safety, Pharmacokinetics, and Pharmacodynamics of VENT-02 Freebase, a CNS-Penetrant NLRP3 Inhibitor. [PDF]

Clin Transl Sci
Smidt LCA, Moerland M, Jansen MAA, Kremer PHC, Sille AAJ, Strugala PK, Klaassen ES, Auger A, Jananji S, Faidi R, Pike KA, Warner L, Matta A, Valencia X, Spiegelstein O.   +14 more
europepmc   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

Human safety of SPBN GASGAS for oral rabies vaccination of dogs. [PDF]

PLoS Negl Trop Dis
Yale G, Freuling C, Gibson A, Gunesekera A, Müller T, Wallace R, Vos A.   +6 more
europepmc   +1 more source

Hierarchical MXene‐Derived NTP/C Nanohybrids for Cryogenic Sodium‐Ion Batteries

Advanced Functional Materials, EarlyView.
A hierarchical MXene‐derived NaTi2(PO4)3/C nanohybrid enables efficient sodium‐ion storage down to −40°C by integrating fast ion–electron transport pathways with an ether‐based electrolyte. The system promotes dominant pseudocapacitive behavior and forms a robust inorganic‐rich SEI, collectively mitigating kinetic and interfacial limitations, thereby ...
M. Sai Bhargava Reddy, Mohammad Zaid, Sayan Das, Sooryadas Sudhakaran, Shampa Aich, Vilas G. Pol   +5 more
wiley   +1 more source

Reviewing the thoroughness of human safety testing for succinate dehydrogenase inhibitors: fluopyram as a case study. [PDF]

Arch Toxicol
Travis KZ, Bars R, Tinwell H.
europepmc   +1 more source

Review of Thermally Activated Twisted Coiled Polymer Actuators: A Materials Science Perspective

Advanced Functional Materials, EarlyView.
Thermally activated twisted and coiled polymer actuators (TCPAs) combine lightweight design, large deformation, and scalable fabrication for soft robotic and wearable applications. This review connects polymer structure, processing history, helix geometry, and thermomechanical characterization to actuator performance, highlighting current challenges in
Nadja Schenk, Lukas Benecke, Chokri Cherif, Johannes Mersch   +3 more
wiley   +1 more source

A self-report study of factors influencing decision-making at rail level crossings: comparing car drivers, motorcyclists, cyclists and pedestrians

, 2013
Collisions at rail level crossings (RLXs) represent a major challenge for both road safety and rail safety professionals. RLX collisions are typically high-severity and high-cost, often involving multiple injuries and/or fatalities as well as major ...
Lenne, M.G., Stanton, Neville A., Stanton, N A, Lenne, M G, Salmon, P M, Beanland, Vanessa, Salmon, P.M., Beanland, V.   +7 more
core  

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

First-in-human safety and pharmacokinetics of MK-7602, the antimalarial inhibitor of plasmepsins IX/X, in single- and multiple-ascending-dose studies. [PDF]

Antimicrob Agents Chemother
Stanley SE, Carstens RP, Liberti MV, Eertmans W, Vranckx M, Longo D, Ghosal N, Vavrek M, Olsen DB, Cowman AF, Reynders T, Cilissen C, Laethem T, Rottey S, Robbins JA, Stoch SA, Nussbaum J.   +16 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source