Results 41 to 50 of about 3,723,142 (300)

Study to evaluate the safety and tolerability of Streptococcus salivarius eK12, a genetically modified strain derived from the oral probiotic S. salivarius K12: Results from a randomized, double-blind, placebo-controlled, parallel-group clinical trial

open access: yesFrontiers in Nutrition
In recent years, genetically engineered probiotics have gained increasing scientific interest owing to their potential applications in human health and nutrition.
Francesco Di Pierro   +14 more
doaj   +1 more source

Refining the mandibular osteoradionecrosis rat model by in vivo longitudinal µCT analysis

open access: yesScientific Reports, 2021
Osteoradionecrosis (ORN) is one of the most feared side effects of radiotherapy following cancers of the upper aero-digestive tract and leading to severe functional defects in patients. Today, our lack of knowledge about the physiopathology restricts the
Morgane Dos Santos   +7 more
doaj   +1 more source

New safety model for the commercial human spaceflight industry [PDF]

open access: yes, 2011
The aviation and space domains have safety guidelines and recommended practices for Design Organisations (DOs) and Operators alike. In terms of Aerospace DOs there are certification criteria to meet and to demonstrate compliance there are Advisory ...
Bond, S.J., Maropoulos, P., Quinn, A.
core  

Impaired contextual modulation of memories in PTSD: an fMRI and psychophysiological study of extinction retention and fear renewal [PDF]

open access: yes, 2014
Post-traumatic stress disorder (PTSD) patients display pervasive fear memories, expressed indiscriminately. Proposed mechanisms include enhanced fear learning and impaired extinction or extinction recall. Documented extinction recall deficits and failure
Abelson, James L   +6 more
core   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Development of a partially supervised Markov decision-making model for a 3-link collaborative robot-manipulator

open access: yesРадіоелектронні і комп'ютерні системи
The subject are mathematical models of decision-making under uncertainty in a production environment with human presence. The research objectives: is to form a safe and effective policy for controlling the motion of a three-link collaborative robot ...
Vladyslav Yevsieiev   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Antioxidants versus Food Antioxidant Additives and Food Preservatives

open access: yesAntioxidants, 2019
Natural and processed foods are fragile and can become unpalatable and/or rotten. The processed food industry uses preservatives to enable distribution, even to different continents, and to extend the useful life of their products.
Rafael Franco   +2 more
doaj   +1 more source

Human Factor in Functional Safety

open access: yesChemical Engineering Transactions, 2010
Abstract preview not available - see full-text PDF article.
openaire   +2 more sources

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