Results 51 to 60 of about 1,366,283 (308)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
NIOSH Public Safety Program [PDF]
"What are our priorities? The National Institute for Occupational Safety and Health (NIOSH) Public Safety Program works with partners in industry, labor, trade associations, professional organizations, and academia.
core +1 more source
Antioxidants versus Food Antioxidant Additives and Food Preservatives
Natural and processed foods are fragile and can become unpalatable and/or rotten. The processed food industry uses preservatives to enable distribution, even to different continents, and to extend the useful life of their products.
Rafael Franco +2 more
doaj +1 more source
Human Factor in Functional Safety
Abstract preview not available - see full-text PDF article.
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Over the years, people in the defense industry and government have used the terms “system safety” and “survivability” interchangeably. The misunderstanding of these terms has created issues when preparing system safety analysis documents, such as ...
Dowd, Joe, Braman, Gary, Dorning, Tyler
core +1 more source
System Theoretic Process Analysis (STPA) is an extremely valuable methodology, especially when used early in a system’s concept phase, for effective and efficient development of safety requirements that address potential safety issues associated with ...
Vernacchia, Mark, Johnston, Jesse
core +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The future of process safety [PDF]
PresentationProcess safety has been practiced for several decades, but it is only in recent years that it has become an established discipline. During this evolution we have seen the development of risk assessment techniques and inherently safer design.
Kerin, Trish
core
Consumer Safety and Pesticide Residues: Evaluating Mitigation Protocols for Greengrocery
The application of pesticides remains a necessary measure for pest management in agriculture, particularly in the cultivation of fruits and vegetables.
Diana Ionela Popescu (Stegarus) +3 more
doaj +1 more source

