Results 71 to 80 of about 1,200,608 (259)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Human Reliability Analysis for Digitized Nuclear Power Plants: Case Study on the LingAo II Nuclear Power Plant

open access: yesNuclear Engineering and Technology, 2017
The main control room (MCR) in advanced nuclear power plants (NPPs) has changed from analog to digital control system (DCS). Operation and control have become more automated, centralized, and accurate due to the digitalization of NPPs, which has improved
Yanhua Zou   +4 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Islamic Principles and UAE Policies Regarding Protecting Senior Citizens’ Rights and Safety

open access: yesSocial Sciences
Islam influences Muslim societies through rules, regulations, and legislation. This paper highlights Islamic principles and legislation that protect the rights and dignity of older adults and compares them to policies and laws that have been applied and ...
Abdulaziz Albrithen   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Impact of Nematicides on Plant-Parasitic Nematodes: Challenges and Environmental Safety [PDF]

open access: yesTunisian Journal of Plant Protection
Tiwari, S. 2024. Impact of nematicides on plant-parasitic nematodes: Challenges and environmental safety. Tunisian Journal of Plant Protection 19 (2): 101-120.
Srijan Tiwari
doaj  

Variation in risk category in methods of calculation of the modified fire load density

open access: yesDyna, 2016
The management of fire safety in buildings is conducted in accordance with the type of use-risk category (Building occupancy code). For Building type XI "libraries and archives" and XII "industrial, workshops and warehouses", the determination of the ...
Cristina Maria Paulo Cadete-Pires   +2 more
doaj   +1 more source

Human freedom and/or safety

open access: yesTemida, 2012
This paper deals with the dilemma of whether it is justified to reduce human freedom and rights in order to achieve a greater level of his personal and / or collective security. The author points to the growing political and criminal repressiveness and fewer guarantees for the respect of human rights and freedoms, all in order to increase ...
openaire   +2 more sources

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

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