Results 81 to 90 of about 3,723,142 (300)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Dynamic Proxemic Model for Human–Robot Interactions Using the Golden Ratio
Applied SciencesThis paper presents a novel approach to determine dynamic safety and comfort zones in human–robot interactions (HRIs), with a focus on service robots operating in dynamic environments with people.
Tomáš Spurný +3 more
doaj +1 more source
Nuclear Engineering and Technology, 2017 The main control room (MCR) in advanced nuclear power plants (NPPs) has changed from analog to digital control system (DCS). Operation and control have become more automated, centralized, and accurate due to the digitalization of NPPs, which has improved
Yanhua Zou +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
International Journal for Research in Applied Science and Engineering TechnologyAbstract: Thisprojectintroducesaninnovativeandroidapplicationdevelopedtoenhancepersonalsafety throughavarietyof critical features. The applicationincludesvoice-activatedemergencyassistance,di- rect access to local emergency services, route management for safer navigation, audio recording capa- bilitiesduringemergencies, andarepositoryof ...
openaire +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Variation in risk category in methods of calculation of the modified fire load density
Dyna, 2016 The management of fire safety in buildings is conducted in accordance with the type of use-risk category (Building occupancy code). For Building type XI "libraries and archives" and XII "industrial, workshops and warehouses", the determination of the ...
Cristina Maria Paulo Cadete-Pires +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Islamic Principles and UAE Policies Regarding Protecting Senior Citizens’ Rights and Safety
Social SciencesIslam influences Muslim societies through rules, regulations, and legislation. This paper highlights Islamic principles and legislation that protect the rights and dignity of older adults and compares them to policies and laws that have been applied and ...
Abdulaziz Albrithen +2 more
doaj +1 more source