Results 101 to 110 of about 9,264,964 (263)

Self-Assembly of Human Serum Albumin: A Simplex Phenomenon

open access: yesBiomolecules, 2017
Spontaneous self-assemblies of biomolecules can generate geometrical patterns. Our findings provide an insight into the mechanism of self-assembled ring pattern generation by human serum albumin (HSA). The self-assembly is a process guided by kinetic and
Garima Thakur   +3 more
doaj   +1 more source

Cabazitaxel-loaded human serum albumin nanoparticles as a therapeutic agent against prostate cancer

open access: yes, 2016
Na Qu,1 Robert J Lee,1,2 Yating Sun,1 Guangsheng Cai,1 Junyang Wang,1 Mengqiao Wang,1 Jiahui Lu,1 Qingfan Meng,1 Lirong Teng,1 Di Wang,1 Lesheng Teng1,3 1School of Life Sciences, Jilin University, Changchun, People’s Republic of China; 2Division ...
Wang M   +9 more
core  

An enzymatic method for the detection of human serum albumin [PDF]

open access: yes, 2001
Albumin is the most abundant protein in human serum. A dye-binding method is commonly used in clinical laboratories for its estimation using different types of dyes. However, all these dye methods were interfered by a variety of compounds.
Javed, M U, Waqar, S N
core  

Binding Sites of Fluorescent Probes on Human Serum Albumin

open access: yes, 1994
Human serum albumin is known to have two major and selective drug binding sites, termed sites I and II. The fluorescent probes, dansylamide and dansylsarcosine selectively interact with sites I and II, respectively.
P Netter, E Drelon, F Lapicque, N Muller
core   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Serum albumin domain structures in human blood serum by mass spectrometry and computational biology

open access: yes, 2017
<p>Contact prediction data generated by EPC-map used in the paper "Serum Albumin Domain Structures in Human Blood Serum by Mass Spectrometry and Computational Biology" by Rappsilber et al.</p ...
Adam Belsom   +9 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Validation of Albumin Prescription in Vali Asr and Ayatollah Musavi Zanjan Hospitals

open access: yesJournal of Pharmacoeconomics and Pharmaceutical Management
Background: Human serum albumin (HSA) is a versatile protein exclusively produced by hepatocyte cells in the liver, constantly released into the bloodstream. Substantial quantities of HSA are employed to ameliorate a variety of clinical conditions.
Rasool Markazi   +4 more
doaj  

The aggregation of "native" human serum albumin

open access: yes, 2015
Recombinant fully deuterated, defatted human serum albumin in heavy water was found to be about 90 % aggregated before final fractionation. For comparison and to establish a datum for this isotope effect, the extent of aggregation is reported for ...
White, John   +6 more
core   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy